Research Project 3

立即测试教育计划(调整)。 项目摘要 非洲裔美国人患结直肠癌(CRC)的发病率和死亡率高于非西班牙裔 白色的。虽然美国各地的结直肠癌死亡率有所下降，但在南部各州，这一数字一直在下降 与其他地区相比，速度较慢。通过增加结直肠癌筛查，可以预防结直肠癌死亡。 流行病学数据表明，与白人相比，非裔美国人的癌症健康状况存在差异。致信地址 针对这些差异，这项研究项目将测试社区卫生顾问(CHA)的有效性 教育干预，以增加对非裔美国人的结直肠癌筛查。根据一项调查的结果 随机试验侧重于对非裔美国人进行结直肠癌筛查，使用个人电话进行患者教育 呼叫和导航有效地将筛查增加了约18%(Cole等人，2017年)。我们的研究 假设是一种创新的CHA干预，使用了国家癌症研究所的改编版本 屏幕可节省材料，将面对面、电话联系和文本消息相结合将增加CRC 未依从者的筛查人数比未接受筛查的对照组高15%或更多 CHA干预。这一假设将通过追求三个具体目标来检验。第一个目标是评估 CHA干预对增加非裔美国人样本中结直肠癌筛查的有效性 他们不了解最新的筛查情况。第二个目的是探讨干预对调解人的影响 以及与接受CRC筛查相关的主持人变量。第三个目标是进行成本- CHA干预效果分析。将从社区中招募两名非裔美国人查德 来进行干预。本研究项目采用随机、双臂、平行研究设计。 比较CHA干预后3个月和12个月接受结直肠癌筛查的效果 干预组与“仅提供信息”的控制组进行比较。主要结果是收到任何 结直肠癌筛查的方式(例如，结肠镜检查或粪便免疫化学测试，适合)。研究人员还将 检查干预的可接受性以及其他指标的变化(知识、自我效能、 意向筛查和儿童权利委员会筛查偏好)。这项研究的潜在影响将是实施 以及传播低成本的干预措施，以增加非裔美国人的结直肠癌筛查， 有效，且易于实施。这一结果将有助于筛查干预措施的研究领域 通过与使用面向临床的方法和其他面向客户的干预措施的其他研究进行比较。 该项目的长期目标是为未来使用多个地点进行的有效性试验提供理由 佛罗里达州经历了儿童权利公约的健康差距，并检查了全系统环境下的实施后勤。

Test Up Now Education Program (TUNE-UP). Project Summary African Americans experience higher incidence and mortality from colorectal cancer (CRC) than non-Hispanic whites. While CRC cancer death rates across the US have declined, in Southern states the decline has been slower compared to other regions. CRC cancer deaths could be prevented with increased CRC screening. Epidemiological data indicate cancer health disparities for African Americans compared to whites. To address these disparities, this research project will test the effectiveness of a Community Health Advisor (CHA) educational intervention to increase CRC screening among African Americans. According to the results of a randomized trial focused on CRC screening for African Americans, patient education using a personal phone call and navigation effectively increased screening by approximately 18% (Cole et al. 2017). Our research hypothesis is that an innovative CHA intervention using an adapted version of the National Cancer Institute Screen to Save materials and combining in-person, phone contact, and text messaging will increase CRC screening among those who are non-adherent by 15% or more compared to a control group who do not receive the CHA intervention. The hypothesis will be tested by pursuing three Specific Aims. The first aim is to evaluate the effectiveness of a CHA intervention for increasing CRC screening among a sample of African Americans who are not up-to-date with screening. The second aim is to explore the effect of the intervention on mediator and moderator variables associated with the receipt of CRC screening. The third aim is to conduct a cost- effectiveness analysis of the CHA intervention. Two African American CHAs will be recruited from the community to deliver the intervention. This research project proposes a randomized, two-arm, parallel study design to compare the effect of a CHA intervention on receipt of CRC screening after three and 12 months in the intervention group compared to an “information-only” control group. The primary outcome is receipt of any modality of CRC screening (e.g., colonoscopy or fecal immunochemical test, FIT). The researchers will also examine acceptability of the intervention as well as changes in other indicators (knowledge, self-efficacy, intention to screen and CRC screening preferences). The potential impact of this study will be the implementation and dissemination of an intervention to increase CRC screening among African Americans that is low-cost, effective, and easily implemented. The results will contribute to the research area of screening interventions through comparisons with other studies using clinic-oriented approaches and other client-oriented interventions. The project’s long-term objective is to provide justification for a future effectiveness trial using multiple sites in Florida experiencing CRC health disparities and examine implementation logistics in system-wide settings.