Pilot and Feasibility Program

摘要-试点和可行性（P&F）计划 P&F计划将继续是中心活动的重要组成部分。在过去的9年里， 作为一个有吸引力的磁铁计划，使研究人员进入系统生物和基础领域， 慢性肾脏疾病的转化研究。从2008年起，该计划资助了18项定期P&F提案- 2017年以及2015-2017年的6笔小额赠款。这包括15个项目，以早期阶段的调查， 这些研究人员实际上仍然积极参与肾脏疾病研究。 获资助的项目涵盖广泛的基础研究、临床研究和转化研究， 人类肾脏疾病该计划的继续将建立在这一成功的基础上，并继续关注 请申请人注意肾脏研究的转化领域。我们将继续灵活处理 该计划通过接受一年期奖学金的申请，并选择申请第二年。我们将 继续鼓励较低成本的奖项，这将使我们能够资助更多的项目，以最大限度地发挥影响。在 此外，还将继续提供利用中心服务的小额赠款。所有申请普通P&F或 建议使用中心核心服务将需要小额赠款。早期研究人员将 优先考虑，但将继续鼓励更多高级调查员的申请， 肾脏研究的转化方法，特别是那些正在初步进军该领域的人。我们 将扩大我们的P&F计划的覆盖范围，包括所有合作临床表型分析的研究人员 所有合作C-PROBE的资源和生物库核心（C-PROBE）研究者和合作者 包括亚利桑那大学的研究人员在内的机构。最后，我们将继续成功的 与其他3个密歇根大学（UM）NIDDK P30中心和密歇根大学的合作安排 临床与健康研究所/转化科学中心奖（MICHR/CTSA），以允许 最好的肾脏P&F赠款的最大资金。所有成功申请者将被录取入读 研究基地，并将要求积极参与本中心活动广告，本计划将 并扩大那些 .

ABSTRACT – PILOT AND FEASIBILITY (P&F) PROGRAM The P&F program will remain a vital component of the Center's activities. Over the past 9 years it has served as an attractive magnet program to bring researchers into the fields of systems biological and basic and translational research of chronic kidney diseases. The program funded 18 regular P&F proposals from 2008- 2017 as well as 6 small grants from 2015-2017. This included 15 projects to early stage investigators, and 3 projects to established investigators, virtually all of whom are still actively involved in kidney disease research. The projects funded covered a wide range of basic through clinical and translational research relevant to human kidney diseases. The continuation of the program will build on this success and continue to focus the attention of applicants on translational areas of kidney research. We will continue the flexibility of the program by taking applications for one-year awards with the option to apply for a second year. We will continue to encourage lower cost awards which will allow us to fund more projects to maximize impact. In addition, small grants that utilize Center services will also be continued. All applicants for either regular P&F or small grants will be required to propose utilization of Center core services. Early stage investigators will be given preference but will continue to encourage applications from more senior investigators embarking on translational approaches to kidney research, especially those who are making initial forays into the area. We will expand the reach of our P&F program to include investigators at all collaborating Clinical Phenotyping Resource and Biobank Core (C-PROBE) investigators and collaborators at all collaborating C-PROBE institutions including investigators at the University of Arizona. Finally, we will continue a successful cooperative arrangement with 3 other University of Michigan (UM) NIDDK P30 Centers and the Michigan Institute for Clinical and Health Research/Center for Translational Science Award (MICHR/CTSA) to allow for maximal funding of the best kidney P&F grants. All successful applicants will be enrolled into the institutional research base and will be required to actively participate in Center activities advertisement for this program will also be expanded .