Administrative Core

行政核心（行政）将作为组织结构，协调 P01，促进其科学使命和外部评估，并促进与UTMB研究的协同作用 程序.行政部的日常运作由Allan Brasier博士指导，他是一位经验丰富、富有成效的 领导人谁带来了相当大的杠杆力量，以促进P01的研究使命。时的情形下 博士Brasier无法或无法对该计划进行监督，Garofalo博士将担任该计划的领导。 管理核心行政管理的主要目标是通过以下方式协助项目负责人（PL）和核心总监：1） 促进项目互动和协同。为确保各组织之间继续进行富有成效的互动， 研究项目（RP）和科学的调整，以这个P01的中心主题，行政协调两次- 每月的研究进展会议和季度业务会议。管理员监控支出，将 必要时重新分配资源，并将促进解决在 进行这些研究。行政人员将进一步促进项目间的沟通，并协助促进 研究设计、统计分析和数据管理。2)提供统计 分析和数据管理。Heidi Spratt博士，一位经过博士培训的生物统计学家，具有以下方面的相关经验： 多变量统计，将与所有三个RP在实验和临床研究的统计方面进行合作 设计、功率计算和数据分析。3)作为NIAID的单一联系点， UTMB赞助项目办公室管理员将负责确保适当合规 遵守UTMB、德克萨斯州、NIH和NIAID的所有政策、法律和法规，以及报告， P01及其项目的财务管理，包括提交文件和项目报告 根据NIAID的要求。4)协调P01外部评审。管理员将与NIAID一起促进现场访问 项目官员，内部咨询委员会（IAC）和外部咨询委员会（EAC），履行其 代表团并将其建议传达给NIH PO和P01 PL。作为本P01的共同研究者， 行政主任将负责执行这些建议。5.整合P01 在UTMB中心和研究所进行哮喘相关研究的RP。行政主任将 确保P01与其他主要UTMB研究实体的持续整合，包括部门， 中心和研究所协调研究项目并开发新项目。在最近的项目中， 在此期间，这些实体一直是智力和资源支持的主要来源， 推进了P01的目标。通过履行这些职能，行政管理将有助于确保继续努力， 实现计划目标，促进内部和外部沟通，并减轻项目领导人的 繁重的行政工作。这将使项目和核心领导人能够自由地追求他们的科学任务 和目标。

The Administrative Core (Admin) will function as the organizational structure that coordinates the activities of the P01, facilitating its scientific mission and external evaluation and promoting synergy with UTMB research programs. Day-to-day operations of Admin are directed by Dr. Allan Brasier, an experienced and productive leader who brings considerable leveraging strength to facilitate the P01’s research mission. In situations when Dr. Brasier is unavailable or unable to provide oversight to the program, Dr. Garofalo will assume leadership of the Admin Core. The major goals of Admin are to assist the Project Leaders (PLs) and Core Directors by: 1) Promoting Project Interactions and Synergy. To ensure continuing productive interactions among the research projects (RPs) and scientific alignment to the central theme of this P01, Admin coordinates twice- monthly research-in-progress meetings and quarterly business meetings. Admin monitors expenditures, will reallocate resources as necessary, and will facilitate resolution of any conflicts that might arise during the conduct of these studies. Admin will further promote inter-project communication and assist in facilitating research design, statistical analysis and data management for all three RPs. 2) Providing Statistical Analysis and Data Management. Dr. Heidi Spratt, a PhD-trained biostatistician with relevant experience in multivariate statistics, will collaborate with all three RPs on statistical aspects of experimental and clinical study design, power calculations, and data analysis. 3) Serving as the Single Point of Contact to the NIAID and the UTMB Office of Sponsored Programs. Admin will be responsible for ensuring appropriate compliance with all policies, laws, and regulations of UTMB, the State of Texas, NIH, and the NIAID, as well as reporting, and fiscal management of the P01 and its projects, including submitting the documentation and project reports required by the NIAID. 4) Coordinating P01 External Reviews. Admin will facilitate site visits with the NIAID Project Officer, Internal Advisory Committee (IAC), and External Advisory Committee (EAC), fulfilling their missions and communicating their recommendations to the NIH PO and the P01 PLs. As co-PI of this P01, the Director of Admin will assume responsibility for implementing these recommendations. 5. Integrating P01 RPs with ongoing asthma-related research in UTMB centers and institutes. The Admin Director will ensure ongoing integration of the P01 with other major UTMB research entities, including Departments, Centers, and Institutes to coordinate research projects and develop new ones. In the most recent project period, these entities have been a major source of intellectual and resource support and have significantly advanced the goals of this P01. By performing these functions, Admin will help to ensure continued efforts towards programmatic goals, facilitate internal and external communications, and relieve project leaders of burdensome administrative activities. This will free the project and core leaders to pursue their scientific tasks and objectives.