Institutional Clinical AND Translational Science Award

整体 项目概要：威斯康星州大学（UW）临床和转化研究所（ICTR） 成立于2007年，在UW的体制变革的背景下，UW医学院 成为医学和公共卫生学院（SMPH，2005年）和其他健康科学 学校重新调整了他们的使命，包括健康维护，预防保健和改善， 保健提供系统。自成立以来，卢旺达问题国际法庭成功地改变了华盛顿大学和华盛顿大学的研究文化。 马什菲尔德诊所（MC），并成为公认的学术和行政家的临床和 转化科学本节概述了卢旺达问题国际法庭最显著的成就， 在行政管理、翻译劳动力教育和扩大 研究基础设施。许多行政上的成功都与相互的发展相一致- 有益的合作关系，包括基础UW和MC伙伴关系，建立 多地点研究网络，跨CTSA方案开发，为卢旺达问题国际法庭提供的联邦和地方各级资金 计划和试点奖励，并与其他华盛顿大学中心和重叠任务计划的隶属关系。 翻译劳动力的发展包括创建有力的TL 1和KL 2培训计划， 临床研究的研究生学位和证书课程，并提供多样化的非学位选择， 学习者在多个层次和轨道。额外的合作努力导致了一个国家认可的计划， 研究导师培训和健康公平领导研究所，职业发展的经验， 从事健康差异/健康公平研究的调查人员。核心事实表明， 华盛顿大学的研究基础设施是卢旺达问题国际法庭的资源和服务支持了约2,500名独立调查员， 研究项目3,824个。卢旺达问题国际法庭为T0-T4翻译项目提供了试点资金， 范围，包括专门针对儿科，老年人和少数民族人群的奖项。协商和其他 专家服务涵盖生物统计学、生物信息学、实验室服务以及一系列临床和监管服务。 服务最后，卢旺达问题国际法庭的社区参与方案被公认为是一个国家模式，说明如何 与社区利益攸关方和组织建立伙伴关系（迄今为止有431个），现在包括 传播和实施方案。值得注意的是，本节还提供了卢旺达问题国际法庭如何- 支持的研究项目已经影响到威斯康星州和全国的医疗保健和健康。在 下一个赠款周期，卢旺达问题国际法庭将继续处理翻译工作人员队伍的发展问题，重点是团队 科学和能力为基础的培训，以及社区参与研究与新的战略， 实施健康进步和患者倡导者的参与。此外，研究 基础设施将通过质量改进和创新周期不断得到改善， 介绍翻译研究的信息学方法。特殊人群研究将是 在T0-T4光谱和整个生命周期中集成。 项目摘要/摘要第126页 联系PD/PI：DREZNER，MARC K 总体- CTSA 自2007年以来，作为NIH临床和转化科学奖计划的成员， 威斯康星州大学（UW）临床和转化研究所（ICTR）是为了提高公众 通过将基础研究发现转化为临床护理和健康的直接，实际改善， 护理提供系统。目前ICTR支持的研究项目已经直接影响到社区 健康在威斯康星州和全国。ICTR代表了五个UW健康科学学校的伙伴关系， 马什菲尔德诊所谁同步工作，以改善研究基础设施，提高当地和多站点 协作研究网络，让患者倡导者和社区利益相关者参与研究，并培训 未来的临床和转化研究人员。

Overall Project Summary: The University of Wisconsin (UW) Institute for Clinical and Translational Research (ICTR) was created in 2007 against a backdrop of institutional change at UW during which the UW Medical School pivoted to become a School of Medicine and Public Health (SMPH, 2005) and the other Health Sciences Schools retooled their missions to encompass health maintenance, preventative care, and improvements in health-delivery systems. Since its inception, ICTR succeeded in changing the culture of research at UW and at Marshfield Clinic (MC) and became recognized as the academic and administrative home for clinical and translational science. This section outlines the most notable ICTR accomplishments leading to transformative changes in the broad areas of administration, education of the translational workforce, and expansion of the research infrastructure. Many of the administrative successes were aligned with development of mutually- beneficial, collaborative relationships including the foundational UW and MC partnership, establishment of multi-site research networks, cross-CTSA program development, braided federal and local funding for ICTR programs and pilot awards, and affiliation with other UW centers and programs with overlapping missions. Translational workforce development included creating vigorous TL1 and KL2 training programs, establishing graduate degree and certificate programs in Clinical Investigation, and offering diverse non-degree options for learners at multiple levels and tracks. Additional collaborative efforts led to a nationally recognized program in research mentor training and the Health Equity Leadership Institute, a career development experience for investigators engaged in health disparities/health equity research. The central fact illustrating the expansion of the UW research infrastructure is that ICTR resources and services supported ~2,500 unique investigators, who have pursued 3,824 research projects. ICTR has provided pilot funding across the T0-T4 translational spectrum including awards specific to pediatric, geriatric, and minority populations. Consultations and other expert services span biostatistics, bioinformatics, laboratory services, and an array of clinical and regulatory services. Finally, the ICTR community engagement program is recognized as a national model for how to create partnerships with community stakeholders and organizations (431 to date) and now includes dissemination and implementation programs. Significantly, this section also provides examples of how ICTR- supported research programs have already impacted health care and health in Wisconsin and nationally. In the next grant cycle, ICTR will continue to address translational workforce development with an emphasis on team science and competency-based training, and community engagement in research with novel strategies for implementation of health advances and involvement of patient advocates. Additionally, the research infrastructure will be continuously improved through cycles of quality improvement and innovation and informatics methods for translational research will be introduced. Special populations research will be integrated across the T0-T4 spectrum and across the lifespan. Project Summary/Abstract Page 126 Contact PD/PI: DREZNER, MARC K Overall - CTSA As a member of the NIH Clinical and Translational Science Awards program since 2007, the mission of the University of Wisconsin (UW) Institute for Clinical and Translational Research (ICTR) is to improve public health by translating basic research discoveries into direct, practical improvements in clinical care and health care delivery systems. Current ICTR-supported research programs have already directly impacted community health in Wisconsin and nationally. ICTR represents a partnership of five UW Health Sciences Schools and Marshfield Clinic who work synchronously to improve research infrastructure, enhance local and multisite collaborative research networks, engage patient advocates and community stakeholders in research, and train the future clinical and translational research workforce.