Component for Institution # 264313

试点项目核心将为新举措和可行性研究提供关键支持，以测试 在药物滥用、疼痛和成瘾领域提出新的假设并产生新的数据 研究，以及滥用药物与艾滋病毒的交叉。受支持的研究范围 在各种学科和技术，包括分子，药理学，生理学， 免疫学和行为学。项目涉及各种药物类别，包括阿片类药物， 大麻素、精神兴奋剂、酒精和尼古丁。支持的数量足以 允许测试新的想法和积累数据，可以用来形成一个基础， 申请外部资金。除了支持该项目的实际资金外， 鼓励研究人员利用研究中心的专业知识和设施， 支持NIDA P30中心的核心。研究支持核心的使用允许那些 开展一个试点项目，通过接受新的技术援助， 他们可能不熟悉的技术和方法，并接受指导， 核心教师。在上一个资助期内，试验计划每年资助三个项目， 核心项目，导致最近授予NIDA R01以及其他提交的赠款 应用程序、若干出版物以及在国家和区域会议上的发言。 潜在的申请人是通过一般和有针对性的公告，在寺教师征求 大学和其他机构的教师通过专业名单服务。申请 试点项目支持由P30中心教师小组委员会评估，并根据 他们的创新和意义的研究问题和方法，概率， 将获得足够的结果作为独立赠款的初步数据 应用程序，并与NIDA P30中心的目标整合的实力。特别 考虑到早期职业调查员和新进入调查领域的调查员， 药物滥用研究通过非正式和频繁的讨论来评估进展情况， 获奖者的进度和正式报告。预计将开展三个试点项目， 每年由核心试点项目直接支持，包括至少两个新项目， 年

The Pilot Project Core will provide critical support for new initiatives and feasibility studies to test new hypotheses and generate novel data in the field of substance abuse, pain and addiction research, and the intersection of drugs of abuse with HIV. Research that is supported ranges over a variety of disciplines and techniques including molecular, pharmacological, physiological, immunological, and behavioral. Projects involve a variety of drug classes including opioids, cannabinoids, psychostimulants, alcohol and nicotine. The amount of support is sufficient to allow the testing of new ideas and accumulating data that can be used to form the basis for an application for external funding. In addition to the actual dollars supporting the project, the investigators are encouraged to make use of the expertise and the facilities of the Research Support Cores of the NIDA P30 Center. Use of the Research Support Cores allows those carrying out a Pilot Project to expand their areas of expertise by receiving assistance with new techniques and approaches with which they may be unfamiliar, and to receive mentoring from the Core faculty. In the previous funding period, three projects/year were supported by the Pilot Projects Core, resulting in a recently awarded NIDA R01 as well as other submitted grant applications, several publications, and presentations at national and regional meetings. Potential applicants are solicited by general and targeted announcements to faculty at Temple University and to faculty of other institutions through professional list-serves. Applications for pilot project support are evaluated by a sub-committee of P30 Center faculty and are judged on their innovation and significance of the research question and approach, the probability that sufficient outcomes will be obtained to serve as preliminary data for an independent grant application, and the strength of the integration with the aims of the NIDA P30 Center. Special consideration is given to early career investigators and to investigators new to the field of substance abuse research. Progress is evaluated via informal and frequent discussions of progress and formal reports from awardees. It is anticipated that three pilot projects will be supported directly by the Pilot Project Core each year, including at least two new projects per year.