Sleep health in special populations

项目总结 睡眠障碍导致的睡眠不足和睡眠质量差会对健康产生负面影响 结果和生活质量。对于有不良预后风险的患者群体来说尤其如此 因为有合并症。虽然有既定的治疗方法和最佳实践来管理睡眠 障碍，包括睡眠呼吸暂停和失眠，在如何最好地管理方面仍然存在重大的知识差距 使患者变得复杂，改善以患者为中心的结果。此应用程序的目标是为 在患者睡眠障碍和睡眠健康领域对实习生和初级调查人员进行指导 处于“危险中”的人群。申请人目前的研究计划主要集中在有睡眠的女性身上 与男性相比，呼吸暂停患者不坚持PAP治疗的风险更高，特别是当他们 在坚持方面面临更多的挑战，例如精神疾病的共病。研究的主要目的是 资助的工作重点是提高妇女对PAP治疗的依从性。其他目标侧重于改进 脊髓损伤患者的PAP依从性和实施改善睡眠的实践 长期护理机构。马丁博士有在不同层次指导受训人员进行研究的记录 独立性，拟议的奖励将增强她为患者提供额外指导的能力 定向研究的重点是睡眠障碍和睡眠健康。该奖项的目标是增加 研究如何最好地治疗睡眠障碍患者的独立临床调查人员的数量 世界“设置。因此，拟议培训计划的目标侧重于向马丁博士提供 实施科学。加州大学洛杉矶分校和退伍军人管理局大洛杉矶医疗系统(VAGLAHS)提供了丰富的 指导和应用临床和卫生服务研究的环境。最后，网络的发展-- 将为临床实习生开发以患者为中心的研究资源，供内部和外部使用 加州大学洛杉矶分校和VAGLAHS。

PROJECT SUMMARY Insufficient and poor quality sleep resulting from sleep disorders can have a negative impact on health outcomes and quality of life. This is particularly true for patient populations who are at risk for poor outcomes due to comorbidities. While there are established treatments and best practices for management of sleep disorders, including sleep apnea and insomnia, significant knowledge gaps remain in how best to manage complex patients and improve patient-centered outcomes. The goal of this application is to provide support for mentoring of trainees and junior investigators in the areas of sleep disorders and sleep health among patient populations who are “at risk.” The applicant's current research program focuses primarily on women with sleep apnea, who are at elevated risk for non-adherence to PAP therapy compared to men, particularly when they face additional challenges to adherence, such as psychiatric comorbidities. The main research aims of the funded work focus on improving adherence to PAP therapy among women. Additional aims focus on improving PAP adherence among patients with spinal cord injuries and on implementing practices to improve sleep in long term care settings. Dr. Martin has a track record of mentoring trainees at multiple levels toward research independence, and the proposed award will enhance her ability to provide additional mentoring in patient oriented research focused on sleep disorders and sleep health. The goal of the award is to increase the number of independent clinical investigators studying how best to treat patients with sleep disorders in “real world” settings. As such, the goals of the proposed training plan focus on providing Dr. Martin with training in implementation science. UCLA and the VA Greater Los Angeles Healthcare System (VAGLAHS) provide rich environments for mentoring and for applied clinical and health services research. Finally, development of web- based resources for clinical trainees in patient oriented research will be developed for use within and beyond UCLA and VAGLAHS.