Affective Dynamics Associated with Simultaneous Alcohol and Marijuana Use Outcomes among a High-risk Sample of Young Adults

项目摘要/摘要 同时使用酒精和大麻(SAM；同时使用这两种物质，以便产生影响 重叠)在美国年轻人中是一个重大的公共卫生问题。近三分之一的年轻人 饮酒者报告了过去一年SAM的使用情况，SAM使用率继续上升。这些上升的利率尤其是 令人担忧的是，因为新出现的数据表明，使用SAM与更糟糕的短期和长期负面影响有关 后果比酒精--只用2-6。因此，迫切需要了解心理社会脆弱性。 与高风险SAM使用相关的因素。消极和积极情感以及情感动态的平均水平(即， 情绪体验如何随时间和情况波动)与以下高风险酒精使用模式相关 年轻人。然而，与SAM使用相关的特定情感脆弱性因素，以及这些因素 与纯酒精使用不同的因素，目前尚不清楚。拟议的F32试图通过以下方式填补文献中的空白 对耗时的日常数据进行二次分析(MPIS：Lee/Patrick；R01AA025037)，以阐明 情感和情感动态在高危成人样本中对SAM使用结果的作用(N=409)。我们 将检验理论上相关的情感动态过程(情感不稳定、消极情绪 差异)：(1)对于预测SAM的使用和酒精的使用，比平均影响水平(在-和 受试者之间)；(2)前瞻性地预测SAM使用和使用相关问题随时间的变化；以及(3) 可以区分SAM的使用和单一物质的使用模式，这对个性化有直接的影响 以及预防和干预努力的精确度。除了解决这些具体目标外，申请人还 将接受以下方面的培训：(1)酒精使用、SAM使用和共生疾病的病因、维持和干预 青壮年心理健康问题；(2)高级定量统计；(3)生态瞬时 评估纵向研究发展和管理；以及(4)专业发展(例如， 手稿和赠款写作)。这项具有成本效益的研究结果可能会对 预防和干预努力，以减少SAM的使用。具体地说，个性化、以技术为基础 干预措施可以包括情绪调节技能培训和即时信息，以帮助那些 SAM使用更多适应性策略来管理情感的风险。

Project Summary/Abstract Simultaneous alcohol and marijuana use (SAM; using both substances at the same time so that effects overlap) is a significant public health concern among young adults in the US. Nearly one-third of young adult drinkers report past-year SAM use and rates of SAM use are continuing to rise1. These rising rates are especially concerning, as emerging data indicate that SAM use is associated with worse short- and long-term negative consequences than alcohol-only use2-6. Thus, there is a critical need to understand psychosocial vulnerability factors related to risky SAM use. Both mean levels of negative and positive affect and affective dynamics (i.e., how emotional experiences fluctuate across time and situations) are related to risky alcohol use patterns among young adults. However, specific affective vulnerability factors associated with SAM use, and whether these factors differ from alcohol-only use, remain unknown. The proposed F32 seeks to fill this gap in the literature by conducting a secondary analysis of time-intensive daily data (MPIs: Lee/Patrick; R01AA025037) to elucidate the roles of affect and affective dynamics on SAM use outcomes among a sample of high-risk adults (N = 409). We will test whether theoretically-relevant affective dynamic processes (affective instability, negative emotion differentiation): (1) are more useful for predicting SAM use and alcohol use than mean level of affect (within- and between-subjects); (2) prospectively predict changes in SAM use and use-related problems over time; and (3) can distinguish SAM use from single substance use patterns, which has direct implications for the personalization and precision of prevention and intervention efforts. In addition to addressing these specific aims, the applicant will receive training in (1) the etiology, maintenance, and intervention of alcohol use, SAM use, and co-occurring mental health problems among young adults; (2) advanced quantitative statistics; (3) ecological momentary assessment longitudinal study development and management; and (4) professional development (e.g., manuscript and grant writing). Findings from this cost-efficient study could have important implications for prevention and intervention efforts to reduce SAM use. Specifically, personalized, technology-based interventions could incorporate emotion regulation skills training and in-the-moment information to help those at risk for SAM use to practice more adaptive strategies to manage affect.