Developing and Testing an Online Intervention for Decreasing Alcohol and Cannabis Misuse and Increasing Healthy Relationship Skills among Young Adult Couples: A Comprehensive Mixed-Methods Approach

开发和测试减少酒精和大麻滥用并提高年轻成年夫妇健康关系技能的在线干预措施：综合混合方法

• 批准号: 10721594
• 负责人: Katherine Walukevich-Dienst
• 金额: $ 17.89万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10721594
• 关键词: Aggressive behavior; Alcohol consumption; Alcohols; Area; Behavior; Cannabis; Communities; Conflict (Psychology); Couples; Data; Data Analyses; Development; Ecological momentary assessment; Educational process of instructing; Etiology; Individual; Intervention; Interview; Knowledge; Learning; Maintenance; Mental Health Services; Mentorship; Methods; Modeling; National Institute on Alcohol Abuse and Alcoholism; Outcome; Participant; Pattern; Persons; Phase; Population; Prevention; Protocols documentation; Public Health; Randomized; Randomized, Controlled Trials; Reporting; Research; Research Personnel; Risk; Self Efficacy; Source; Surveys; Testing; Time; Training; Treatment Efficacy; Treatment outcome; acceptability and feasibility; alcohol abuse therapy; brief alcohol intervention; brief intervention; career; cohort; comparison control; efficacy testing; experience; feasibility testing; follow-up; high risk; high risk population; improved; innovation; intervention delivery; intervention refinement; intimate behavior; mHealth; marijuana use; multilevel analysis; novel; online intervention; patient engagement; preservation; prototype; satisfaction; sex; skills; social; social influence; social stigma; substance misuse; substance use; trial design; user centered design; young adult

Project Abstract Co-use of alcohol and cannabis (using both substances, either simultaneously or concurrently) represents a significant public health concern among young adults (YAs), as co-use of these substances is common and worsens alcohol-related harms. However, YAs are unlikely to seek treatment for their substance use, and existing brief interventions (BIs) for alcohol and cannabis misuse produce modest effects. Thus, there is a critical need to explore novel treatment components to increase participant engagement and maximize effects. From a social-developmental perspective, romantic partners have the strongest social influence on YA substance use, and an underexplored area for intervention. Dyadic research suggests romantic couples mutually influence each other’s substance use, increasing risk for greater substance use involvement and more negative interpersonal consequences. Whether these associations extend to or are exacerbated by co- use remains understudied. Crucially, there is no known BI for co-use among YA couples. This innovative study seeks to fill these gaps in two phases. Phase 1a: 75 YA couples will provide 30 days of daily reports on alcohol and cannabis use, co-use, negative (e.g., conflict) and positive interpersonal consequences (e.g., intimacy), and relationship outcomes (e.g., satisfaction). Multilevel models will test whether a person’s co-use is associated with a greater likelihood of their partner co-using. Multilevel Actor Partner Independence Models will test if couples experience greater negative consequences, fewer positive consequences, and poorer relationship functioning on days when both partners report co-use than on days when only one partner reports co-use, and vice versa (consequences → next day co-use). Phase 1b: 15 participants from Phase 1 will participate in qualitative interviews to assess treatment need and inform intervention content. Data and rapid prototyping (Phase 1 c) will inform development of an online, couples- based BI aimed at decreasing co-use and promoting healthy relationship skills. Phase 2: A second cohort of co-using YA couples will be randomly assigned to the intervention (n = 15 couples) or control (n = 15 couples) and complete baseline, post-assessment, and 3-month follow-up surveys testing feasibility, acceptability, and initial support. Completing this research will support my development as an independent alcohol and cannabis researcher with a focus on developing novel interventions for high-risk YA populations. To achieve my career objectives, I require additional training in 1) social-interpersonal influences that impact etiology, maintenance, and treatment of alcohol and cannabis use among YAs in romantic relationships, 2) couples-based intervention delivery, 3) dyadic ecological momentary assessment research and dyadic data analysis, 4) user-centered design, and 5) randomized control trial (RCT) design. The project will provide pilot data for an R01 submission to NIAAA which will test efficacy of the intervention in a full-size RCT.

项目摘要 同时使用酒精和大麻(同时或同时使用两种物质)是一种 年轻人对公共卫生的重大关切，因为共同使用这些物质很常见，而且 加重与酒精有关的伤害。然而，Yas不太可能为他们的药物使用寻求治疗，以及 现有的对酒精和大麻滥用的短暂干预(BIS)效果不大。因此，有一个 迫切需要探索新的治疗成分，以提高参与者的参与度并最大限度地发挥效果。 从社会发展的角度来看，浪漫伴侣对YA的社会影响最大 物质使用，以及未被开发的干预领域。二元研究表明浪漫的情侣 相互影响彼此的物质使用，增加更多参与物质使用的风险 更多的负面人际后果。无论这些联系是否延伸到或被共同- 对它的使用研究还不够深入。至关重要的是，目前还没有已知的BI在YA夫妇中共同使用。 这项创新的研究试图通过两个阶段来填补这些空白。第一阶段：75对YA夫妇将提供30天 关于酒精和大麻的使用、共同使用、消极的(如冲突)和积极的人际关系的每日报告 结果(例如，亲密)和关系结果(例如，满意度)。多层模型将测试 一个人的共同使用是否与其伴侣共同使用的可能性更大有关。多层次执行者 伴侣独立性模型将测试夫妻是经历更多的负面后果，还是更少的积极后果 结果，当双方都报告共同使用时，关系运作会比当天更差 当只有一个合作伙伴报告共同使用时，反之亦然(Resuctions→翌日共同使用)。1B期：15 第一阶段的参与者将参加定性访谈，以评估治疗需求并告知 干预内容。数据和快速成型(阶段1 c)将为在线夫妇的开发提供信息- 基于商业智能的目的是减少共同使用，促进健康的人际关系技能。阶段2：第二批 共同使用YA的夫妇将被随机分配到干预组(n=15对)或对照组(n=15对) 并完成基线、评估后和3个月的跟踪调查，以测试可行性、可接受性和 最初的支持。完成这项研究将支持我成为一名独立的酒精和大麻 研究人员，专注于为YA高危人群开发新的干预措施。为了成就我的事业 目标，我需要额外的培训：1)影响病因学、维护、 以及在恋爱关系中使用酒精和大麻的治疗，2)基于夫妇的干预 交付，3)二元生态瞬时评估研究和二元数据分析，4)以用户为中心 设计；5)随机对照试验设计。该项目将为R01提交提供试点数据 NIAAA将在全尺寸随机对照试验中测试干预的效果。