Developing and Testing an Online Intervention for Decreasing Alcohol and Cannabis Misuse and Increasing Healthy Relationship Skills among Young Adult Couples: A Comprehensive Mixed-Methods Approach

工程摘要 同时使用酒精和大麻（同时或同时使用这两种物质）是一种 年轻人（YAs）中的重大公共卫生问题，因为共同使用这些物质是常见的， 酒精相关的危害。然而，青少年不太可能寻求治疗他们的物质使用， 现有的针对酒精和大麻滥用的短期干预措施效果有限。因此，有一个 迫切需要探索新的治疗成分，以提高参与者的参与度并最大限度地提高效果。 从社会发展的角度来看，浪漫的伴侣对YA的社会影响最大 物质使用，以及一个未充分探索的干预领域。二元研究表明，浪漫的夫妇 相互影响彼此的物质使用，增加更多物质使用参与的风险， 更多的负面人际影响。无论这些关联是否延伸到或加剧了共同- 使用仍然研究不足。至关重要的是，在YA夫妇中没有已知的BI共同使用。 这项创新研究旨在分两个阶段填补这些空白。第1a阶段：75对YA夫妇将提供30天的时间 关于酒精和大麻使用、共同使用、负面（例如，积极的人际关系 后果（例如，亲密度），和关系结果（例如，满意度）。多层次模型将测试 一个人的共同使用是否与他们的伴侣共同使用的可能性更大有关。多级执行元 伴侣独立模型将测试伴侣是否经历更多的负面后果，更少的正面后果。 结果，和较差的关系运作的日子，双方合作伙伴报告共同使用比天 只有一个伴侣报告共同使用，反之亦然（后果→第二天共同使用）。1b期：15例 第1阶段的参与者将参加定性访谈，以评估治疗需求并告知 干预内容。数据和快速原型（第1c阶段）将为在线夫妇的开发提供信息- 基于BI旨在减少共同使用和促进健康的关系技能。第二阶段：第二批 共同使用YA的夫妇将被随机分配到干预组（n = 15对夫妇）或对照组（n = 15对夫妇） 并完成基线、评估后和3个月随访调查，测试可行性、可接受性和 初步支持。完成这项研究将支持我作为一个独立的酒精和大麻的发展 研究人员专注于为高风险YA人群开发新的干预措施。为了成就我的事业 目标，我需要额外的培训1）社会人际影响，影响病因，维护， 在浪漫关系中使用酒精和大麻的青少年的治疗，2）基于夫妇的干预 2）生态瞬时评价研究和数据分析; 4）以用户为中心 随机对照试验（RCT）设计。该项目将为R 01提交资料提供试验数据 NIAAA将在全尺寸RCT中测试干预的有效性。

Project Abstract Co-use of alcohol and cannabis (using both substances, either simultaneously or concurrently) represents a significant public health concern among young adults (YAs), as co-use of these substances is common and worsens alcohol-related harms. However, YAs are unlikely to seek treatment for their substance use, and existing brief interventions (BIs) for alcohol and cannabis misuse produce modest effects. Thus, there is a critical need to explore novel treatment components to increase participant engagement and maximize effects. From a social-developmental perspective, romantic partners have the strongest social influence on YA substance use, and an underexplored area for intervention. Dyadic research suggests romantic couples mutually influence each other’s substance use, increasing risk for greater substance use involvement and more negative interpersonal consequences. Whether these associations extend to or are exacerbated by co- use remains understudied. Crucially, there is no known BI for co-use among YA couples. This innovative study seeks to fill these gaps in two phases. Phase 1a: 75 YA couples will provide 30 days of daily reports on alcohol and cannabis use, co-use, negative (e.g., conflict) and positive interpersonal consequences (e.g., intimacy), and relationship outcomes (e.g., satisfaction). Multilevel models will test whether a person’s co-use is associated with a greater likelihood of their partner co-using. Multilevel Actor Partner Independence Models will test if couples experience greater negative consequences, fewer positive consequences, and poorer relationship functioning on days when both partners report co-use than on days when only one partner reports co-use, and vice versa (consequences → next day co-use). Phase 1b: 15 participants from Phase 1 will participate in qualitative interviews to assess treatment need and inform intervention content. Data and rapid prototyping (Phase 1 c) will inform development of an online, couples- based BI aimed at decreasing co-use and promoting healthy relationship skills. Phase 2: A second cohort of co-using YA couples will be randomly assigned to the intervention (n = 15 couples) or control (n = 15 couples) and complete baseline, post-assessment, and 3-month follow-up surveys testing feasibility, acceptability, and initial support. Completing this research will support my development as an independent alcohol and cannabis researcher with a focus on developing novel interventions for high-risk YA populations. To achieve my career objectives, I require additional training in 1) social-interpersonal influences that impact etiology, maintenance, and treatment of alcohol and cannabis use among YAs in romantic relationships, 2) couples-based intervention delivery, 3) dyadic ecological momentary assessment research and dyadic data analysis, 4) user-centered design, and 5) randomized control trial (RCT) design. The project will provide pilot data for an R01 submission to NIAAA which will test efficacy of the intervention in a full-size RCT.