ADVANCING INFECTIOUS DISEASES DETECTION AND RESPONSE IN INDONESIA THROUGH IMPROVING PUBLIC HEALTH LABORATORY CAPACITY

项目摘要 该提案的目的是在以下地区开展高质量的公共卫生研究项目： 这将有助于确定国家和国家以下各级的卫生政策。第1 今年，这些项目将侧重于： 1.了解医院获得性感染（HAI）的患病率， 印度尼西亚高质量的抗菌素耐药性（AMR）监测。该项目将 使卫生部能够确定HAI的患病率，其结果将用于协助 规划感染预防和控制干预措施以及病例管理。 此外，结果将支持卫生部制定标准化和知情的 应对印度尼西亚的HAI; 2.检测印度尼西亚关注的重点传染病，并评估 通过建立新的实验室能力进行诊断化验。最初 这项研究的主要重点将是疟疾，这项研究的具体目标是 确定一个目标地区的疟原虫流行率，并评估RDT 利用血清学技术诊断疟疾; 3.评估国家参考实验室、省级和地区实验室所需的能力 加强实验室系统，以有效检测、测试、诊断和 报告对印度尼西亚具有重要意义的某些易流行疾病。成果 研究将用于提供建议和制定战略，以改善 印度尼西亚的实验室检测能力和样本转介系统。

PROJECT SUMMARY The purpose of this proposal is to conduct high quality public health research projects in Indonesia that will be beneficial in defining national and sub-national health policies. In the 1st year, the projects will focus on: 1. Understanding the prevalence of hospital acquired infections (HAIs) toward establishing a high-quality antimicrobial resistance (AMR) surveillance in Indonesia. This project will enable MoH to identify the prevalence of HAI and the results will be used to assist the planning for infection prevention and control interventions and case management. Additionally, results will support the MOH to develop a standardized and informed response to address HAIs in Indonesia; 2. Detecting priority infectious diseases of interest to Indonesia as well as evaluate diagnostic assays through the establishment of novel laboratory capacity. Initially, the primary focus of this study will be on malaria and the specific aims of this study are to determine the prevalence of Plasmodium in one targeted area and to evaluate the RDT for the diagnosis of malaria using serology techniques; 3. Evaluating the capacity needed at national reference, provincial, and district laboratories to strengthen laboratory systems for the effective detection, testing, diagnosis, and reporting of selected epidemic prone diseases of importance to Indonesia. Results of this study will be used to provide recommendations and develop a strategy to improve the laboratory testing capacity and sample referral system in Indonesia.