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中文摘要
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项目总结/摘要 埃默里大学的肺癌SPORE旨在促进早期职业肺癌的发展 通过职业提升计划(CEP)的实施,调查人员。拟议的肺的目标 癌症孢子CEP是为学术医生,科学家,临床医生, 研究人员和实验室的科学家谁希望致力于转化研究, 肺癌的诊断、成像、预防、治疗和改善生活质量, 增强肺癌研究界的多样性。SPORE CEP将建立在强大的 埃默里温希普癌症研究所和相关的医学院部门的承诺, 初级调查员的职业发展,其中包括18名职业发展计划获奖者, 埃默里大学以前的头颈癌孢子和正在进行的T32分子肿瘤学培训补助金。 拟议的CEP旨在提供一个环境,使有才华的早期职业调查人员能够从事 一个为期2年的指导研究计划,以促进他们的成功和他们的学术生涯发展, 获得独立研究者地位。CEP的具体目标如下:目标1:吸引 并指导一组有才华的早期职业研究人员从事转化型肺癌研究; 目标2:让埃默里大学的生物学家、科学家和医生以及当地合作伙伴参与研究 目的3:加强格鲁吉亚州转化型肺癌研究机构的多样性, 肺癌研究社区,鼓励少数民族个人,妇女和残疾人, 申请CEP支持;目标4:促进和指导生物学研究的新兴策略, 预防和长期治疗肺癌。平均每年资助2个项目。额外 埃默里大学温希普癌症研究所的配套资金已经为CEP提供了支持 医学院和伍德拉夫健康科学中心。
英文摘要
PROJECT SUMMARY/ABSTRACT Emory University’s Lung Cancer SPORE aims to promote the advancement of early career lung cancer investigators through the conduct of a Career Enhancement Program (CEP). The goals of the proposed Lung Cancer SPORE CEP are to provide training and guidance for academic physician-scientists, clinician- investigators, and laboratory-based scientists who wish to dedicate their efforts to translational research in the areas of diagnosis, imaging, prevention, treatment, and improvement in quality of life in lung cancer, and to enhance diversity among the lung cancer research community. The SPORE CEP will build on the strong commitment of the Emory Winship Cancer Institute and the associated School of Medicine Departments to the career development of junior investigators, which has included 18 career development program awardees as part of Emory’s previous head and neck cancer SPORE and an ongoing T32 training grant in molecular oncology. The proposed CEP aims to provide an environment that enables talented early career investigators to engage in a 2-year mentored research program and to facilitate their success and their academic career development in terms of achieving independent investigator status. Specific aims for the CEP are as follows: Aim 1: To attract and mentor a talented group of early career investigators towards a career in translational lung cancer research; Aim 2: To engage biologists, scientists and physicians present at Emory University and local partner research institutions in the state of Georgia in translational lung cancer research; Aim 3: To enhance diversity among the lung cancer research community by encouraging minority individuals, women, and individuals with disabilities to apply for CEP support; and Aim 4: To foster and guide emerging strategies for the study of the biology, prevention and long term treatment of lung cancer. On average, 2 projects will be funded annually. Additional support for the CEP has been secured from matching funds from the Winship Cancer Institute, Emory University School of Medicine and the Woodruff Health Sciences Center.
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Project 3: Inhibiting FAK to enhance immune checkpoint inhibitor therapy in LKB1-mutant lung adenocarcinoma
  • 批准号:
    10411668
  • 项目类别:
  • 资助金额:
    $54.89万
  • 财政年份:
    2022
  • 负责人:
    Adam I. Marcus
  • 依托单位:
Cleared Tissue Large FOV Microscope Request
  • 批准号:
    10429884
  • 项目类别:
  • 资助金额:
    $30.84万
  • 财政年份:
    2022
  • 负责人:
    Adam I. Marcus
  • 依托单位:
Project 3: Inhibiting FAK to enhance immune checkpoint inhibitor therapy in LKB1-mutant lung adenocarcinoma
  • 批准号:
    10631151
  • 项目类别:
  • 资助金额:
    $56.99万
  • 财政年份:
    2022
  • 负责人:
    Adam I. Marcus
  • 依托单位:
Implications of metabolic heterogeneity on collective lung cancer cell invasion
  • 批准号:
    10383657
  • 项目类别:
  • 资助金额:
    $44.14万
  • 财政年份:
    2021
  • 负责人:
    Adam I. Marcus
  • 依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: