Administrative Core

项目摘要-管理核心 行政核心将提供必要的监督，以首先在变革性地建立中心 在科布雷第一阶段阿拉斯加大学的新陈代谢研究，然后将确保长期 中心在所有三个科布雷阶段及以后的可持续性。行政的领导力 核心有两种形式：行政性和科学性。中心主任凯利·德鲁博士将领导行政管理 组件。科学领导和专业建议由外部咨询委员会分享 成员、翻译咨询委员会成员、总统教授和NIH资助 顾问/合作者。德鲁博士是全国公认的冬眠和新陈代谢研究领域的领导者， C-Trim的科学重点，并拥有丰富的管理和指导经验。外在的 咨询委员会将协助德鲁博士做出与C-TRIM相关的监督决定，并指导学院 发展计划，将增强调查人员竞争互补NIH个人的能力 研究补助金或其他同等的外部支助，并确保C形装饰作为一个专题的寿命， 多学科、最先进的新陈代谢研究中心。科布雷第一阶段的短期目标 就是要通过对中心实施行政监督，为实现长远目标奠定基础， 执行C-TRIM项目负责人的教师发展计划，建立高效、高效的学院 核心设施，监督试点项目计划，以促进中心初级教师的成长和 对进展情况进行批判性评估。为了实现C-Trim的长期和短期目标， 中心领导层将在行政核心中追求以下具体目标：SA1。创建一个支持性的 为基础科学家和转化型科学家提供培训和建议的环境。SA2.建立两项新的技术 支持中心科学目标的核心。SA3.定义基础科学研究的转换路径 哺乳动物冬眠状态SA4。管理和执行试点项目计划。完成C形修剪后 将是美国第一个将冬眠作为自然适应模型的生物医学研究中心 代谢作为解决代谢性疾病治疗中复杂临床问题的一种方法。

Project Summary -Administrative Core The Administrative Core will provide the oversight necessary to first establish the Center in Transformative Research in Metabolism at the University of Alaska during COBRE Phase I and then will ensure the long-term sustainability of the center through all three COBRE Phases and beyond. Leadership of the Administrative Core takes two forms: administrative and scientific. The Center Director, Dr. Kelly Drew, will lead administrative components. Scientific leadership and professional advising is shared by the External Advisory Committee members, the Translational Advisory Committee members, President's Professors and NIH-funded advisors/collaborators. Dr. Drew is a nationally recognized leader in the study of hibernation and metabolism, the scientific focus of the C-TRiM and has extensive administrative and mentoring experience. The External Advisory Committee will assist Dr. Drew in C-TRiM-related oversight decisions and guide the Faculty Development Plans that will enhance the ability of investigators to compete for complementary NIH individual research grants or other equivalent extramural support, and ensure the longevity of the C-TRiM as a thematic, multi-disciplinary, state-of-the-art research center in metabolism. The short- term goal for the Phase I COBRE is to lay the foundation for achieving the long-term goal by implementing administrative oversight of the center, executing the Faculty Development Plans for the C-TRiM Project Leaders, establishing productive and efficient Core Facilities, overseeing a Pilot Project Program to seed the growth of junior faculty in the center and providing critical evaluation of progress. To achieve the long-term and short-term goals of the C-TRiM, the center leadership will pursue the following Specific Aims in the Administrative Core: SA1. Create a supportive environment for the training and advising of basic and translational scientists. SA2. Establish two new technical cores to support scientific goals of the Center. SA3. Define translational paths for basic science research in mammalian hibernation SA4. Manage and administer the Pilot Project program. When complete the C-TRiM will be the first biomedical research center in the US to adopt hibernation as a model of natural adaptations in metabolism as an approach to solve complex clinical problems in the treatment of metabolic disease.