Training Program in Chemosensory Science

摘要 这项T32机构国家研究科学奖提案的总体目标是支持博士后 通过化学感官科学(TPC)培训计划进行的化学感官研究培训 佛罗里达大学。对化学感官(嗅觉、味觉、化学合成和内在感官)的研究 化学传感)对人类健康具有广泛的影响，包括：嗅觉或味觉损伤的影响(例如， 嗅觉障碍、幻觉等)关于饮食、营养、安全、人际关系和发病率的研究 抑郁症；正常气味和味道的参与，以促进健康饮食； 对过度消费及其相关疾病(如糖尿病、 高血压等)；以及通过中断寄主寻找或 繁殖。不幸的是，化学传感科学家拥有适当的方法专长和 这一多学科领域的必要知识仍然短缺。这种需求创造了一个强大的 建立一体化的化学传感科学博士前培训计划的动力。化学感官 佛罗里达大学的研究界-在研究问题和方法上高度多样化，但 通过UF嗅觉和味觉中心进行组织和整合-处于领先地位的独特位置 TPC计划有四个具体目标：(1)成功地开展博士前培训计划 化学感官科学由一门教学课程组成，以一系列化学感官研究为重点 讨论、有指导的研究体验、患者外展体验和专业发展；(2) 将博士前实习生与强大的研究导师和经验丰富的多学科委员会联系起来 调查人员；(3)从国家和地方的合格候选人库中招聘有才华和多样化的受训人员； 以及(4)根据博士前项目的教育目标对该项目进行评估。这 续签申请寻求为TPC提供五年的资金，以支持每年四名博士前学生(两名 每名受训者两年的培训支持)，目的是培养能够 在嗅觉、味觉和化学合成科学方面做出了重大贡献。在这段时间结束时 在支持下，一群不同的博士前实习生将接受指导并教授先进的方法， 基础知识，以及进一步开展化学传感研究所需的多学科方法。 总之，该计划提供了化学感官科学的全面培训，将有效地准备 我们的受训人员提供了丰富的化学传感科学职业。

ABSTRACT The overall goal of this T32 Institutional National Research Science Award proposal is to support predoctoral training in chemical senses research through the Training Program in Chemosensory Science (TPCS) at the University of Florida. The study of the chemical senses (smell, taste, chemesthesis and internal chemosensing) has broad impacts on human health, including: the effects of smell or taste impairments (e.g., anosmia, phantom tastes, etc.) on eating, nutrition, safety, interpersonal relationships and the incidence of depression; the engagement of normal smell and taste to promote healthy eating; the contribution of maladaptive chemosensory behaviors to overconsumption and its related diseases (e.g., diabetes, hypertension, etc.); and the control of disease vectors and parasites through disruption of host seeking or reproduction. Unfortunately, chemosensory scientists with the appropriate methodological expertise and requisite knowledge in this multidisciplinary field continue to be in short supply. This need creates a strong impetus for building an integrative predoctoral training program in chemosensory science. The chemosensory research community at the University of Florida – highly diverse in research questions and methodologies, but organized and integrated through the UF Center for Smell and Taste – is uniquely positioned to lead this program.The TPCS has four Specific Aims: (1) To conduct a successful program of predoctoral training in chemosensory science composed of a didactic curriculum, a series of chemical senses research-focused discussions, a mentored research experience, a patient outreach experience, and professional development; (2) To link predoctoral trainees with strong research mentors and a multidisciplinary committee of experienced investigators; (3) To recruit talented and diverse trainees from national and local pools of eligible candidates; and (4) To evaluate the program in terms of educational objectives tailored to the pre-doctoral program. This renewal application seeks five years' funding for the TPCS to support four predoctoral students per year (two in each of two years of training support per trainee) with the aim of producing independent scientists capable of making significant contributions to the science of smell, taste and chemesthesis. At the conclusion of the period of support, a diverse group of predoctoral trainees will have been mentored and taught the advanced methods, fundamental knowledge, and multidisciplinary approaches necessary to further chemosensory research. Together, this program provides a comprehensive training in chemosensory science that will effectively prepare our trainees for the wealth of chemosensory science careers available.