Using MVRDL to increase the FDA Vet-LRN sample analysis capacity during animal food/feed emergency events

项目摘要 密西西比州兽医研究和诊断实验室(MVRDL)是一项全方位的服务，AAVLD认证， 所有物种，中心参考实验室。我们的工作人员包括10名教职员工(病理学家、家禽 兽医、微生物学家、病毒学家和分子生物学家)和大约28个工作人员职位。 微生物科人员由一名科长(DVM、硕士和兽医博士)组成 理科)，拥有30多年的临床和微生物学研究经验，实验室协调员 拥有25年的微生物学经验和两名具有10年以上临床工作经验的医疗技术员 每个人都有实验室经验。该部门每年分析大约3000份材料的样本， 其中有9000多个程序(需氧培养、厌氧培养、药敏试验) 完成。 分子诊断科人员由一名科长(动物营养学硕士和博士)组成 和兽医)拥有7年以上的临床和分子诊断研究经验 经验，两名具有15年以上分子诊断经验的实验室技术员，一名 具有1年分子诊断经验的实验室技术员。这一部分分析了2500多个 每年完成6000多个程序(聚合酶链式反应和基因测序)。 通过参与这项合作协议，我们同意参与三个关键项目领域： (1)参与FDA/Vet-LIRN样品分析 (2)为潜在的监管用途提供分析数据 (3)参与小规模方法开发、方法验证和矩阵扩展工作 由VPO确定。 MVRDL作为Vet-LIRN抗菌素耐药性和全基因组的来源实验室参与 对项目进行排序。 MVRDL有能力并愿意提供其服务，以提高VPO的处理能力 增加了紧急情况下的样本工作流程。MVRDL致力于在一个 此外，委员会还要求以高效、准确和及时的方式进行调查，并向所需机构报告调查结果。

Project Summary The Mississippi Veterinary Research and Diagnostic Laboratory (MVRDL) is a full service, AAVLD accredited, all species, central reference laboratory. Our work force includes 10 faculty members (pathologists, poultry veterinarians, microbiologists, virologists, and molecular biologists) and approximately 28 staff positions. The Microbiology section personnel consists of a section supervisor (DVM, MS and PhD in Veterinary Sciences) with more than 30 years of clinical and research microbiology experience, a laboratory coordinator with 25 years of microbiology experience and two medical technologists with over 10 years of clinical laboratory experience each. The section analyzes samples from approximately 3000 accessions per year from which over 9000 procedures (aerobic cultures, anaerobic cultures, antimicrobial susceptibility tests) are completed. The Molecular Diagnostics section personnel consists of a section supervisor (MS and PhD in Animal Nutrition and Veterinary Medical Science) with more than 7 years of clinical and research molecular diagnostic experience, two laboratory technologists with more than 15 years of molecular diagnostic experience, and one laboratory technologist with 1year of molecular diagnostic experience. The section analyzes over 2500 accessions per year from which over 6000 procedures (PCR and gene sequencing) are completed. Through our participation in this collaborative agreement, we agree to participate in the three key project areas: (1) Participation in FDA/Vet-LIRN sample analysis (2) Providing analytical data for potential regulatory use (3) Participation in small-scale method development, method validation and matrix extension work as determined by the VPO. The MVRDL participates as a source lab for the Vet-LIRN antimicrobial resistance and whole genome sequencing projects. MVRDL has the capacity and is willing to offer its’ services to increase the capacity of the VPO in handling increased sample workflow during emergencies. MVRDL is committed to performing these services in an efficient, accurate and timely fashion and to reporting the results to the required agency.