Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)

摘要-修改为行政副刊，带下划线 在中西部农村地区爆发的艾滋病毒和丙型肝炎病毒与共用注射器有关 注射非医疗处方阿片类药物的伴侣。伊利诺伊州是百分比第三高的州 2014-2015年间，涉及合成鸦片类药物的死亡率上升。最南端的16个县 伊利诺伊州包括伊利诺伊州三角洲地区(IDR)，并分享了农村地区的许多特征 经历了最近的艾滋病毒流行。更深入地了解社区特征，包括过渡 从口服到注射阿片类药物的使用，高风险注射做法的情况，种族的影响和影响 结构性种族主义，以及异性恋主义和顺性别主义，包括获得现有和潜在的 与卫生有关的资源将是发展疾病预防和治疗模式的关键。 与州和地方公共卫生其他州机构、基于社区的项目、地方联盟 和医疗保健系统，我们将采用混合分析方法，使用预测建模、地理信息系统分析、 定性和调查分析、网络方法和传染病流行病学的理解 地理空间和社会文化因素影响IDR注射吸毒者的健康结果。 在本增刊中，我们将与黑人、性少数和/或性别少数群体发展有意义的伙伴关系 (SGM)确定研究区域内的社区，以确保共享目标、优先事项和流程 毒品使用和减少危害研究的背景和增加黑人和SGM识别的招募 个体融入家长伦理研究。我们将完善现有的仪器，确保最佳勘探 以及潜在的社会、文化和医疗/结构性药物使用引进和继续使用的背景 途径、药物类型、给药途径、共享行为、药物使用网络以及知识和 对减少危害和成瘾治疗的认识、可接受性和利用，特别注重 黑人和SGM确定社区的显著因素。这些数据将以证据为基础，在文化上 有效和包容性的干预措施，以加强获得疾病筛查和与保健和医疗服务的联系 治疗，扩大针头交换和纳洛酮过量方案，筛查和转介 物质使用治疗和远程保健能力建设，以提供PrEP、丙型肝炎病毒管理和 药物辅助治疗药物使用障碍。

ABSTRACT – Modified for administrative supplement, underlined Outbreaks of HIV and HCV in rural areas of the Midwest have been associated with syringe-sharing among partners injecting nonmedical prescription opioids. Illinois ranks as the third highest state in percentage increase in death rates involving synthetic opiates between 2014-2015. The southernmost 16 counties of Illinois comprise the Illinois Delta Region (IDR) and share many of the characteristics of rural areas that have experienced recent HIV epidemics. A deeper understanding of community characteristics, including transitions from oral to injection opioid use, circumstances for high-risk injection practices, impact of race and the effects of structural racism, as well as heterosexism and cisgenderism including accessibility to existing and potential health-related resources will be essential to developing models of disease prevention and treatment. Partnering with state and local public health other state agencies, community-based programs, local coalitions and healthcare systems, we will take a mixed analytical approach using, predictive modeling, GIS analysis, qualitative and survey analysis, network methods, and infectious disease epidemiology to understand geospatial and sociocultural factors impacting health outcomes in people who inject drugs in the IDR. In this supplement we will develop meaningful partnerships with Black and sexual and/or gender minority (SGM) identifying communities in the study area to ensure shared goals, priorities, and processes within the context of drug use and harm reduction research and increase recruitment of Black and SGM identifying individuals into the ETHIC parent study. We will refine current instruments to ensure the optimal exploration and contextualization of potential social, cultural, and medical/structural drug use introduction and continuation pathways, drug types, routes of administration, sharing behaviors, drug use networks, and knowledge and awareness, acceptability, and utilization of harm reduction and addiction treatment with particular focus on salient factors for Black and SGM identifying communities. These data will inform evidence-based, culturally competent and inclusive interventions to strengthen access to disease screening and linkage to care and treatment, expansion of needle exchange and naloxone overdose programs, screening and referral to substance use treatment, and telehealth capacity building for the provision of PrEP, HCV management, and medication-assisted treatment for substance use disorder.