Optimizing Technology Uptake and Use in Hard to Reach Adolescents with Type 1 Diabetes

项目摘要/摘要 患有1型糖尿病(T1D)的青少年(10-15岁)血糖控制恶化的风险很高 以及相对较差的整体T1D自我管理能力。连续血糖监测仪(CGM)提供实时 它可以显示血糖水平，并提醒用户注意低血糖和高血糖。一致、知情地使用 CGM有可能改善血糖控制和相关的T1D健康结局。然而，青少年 患有T1D的人是最不可能使用CGM的年龄段，在获得和 在有种族和少数族裔背景的青年以及有公共保险的青年中使用CGM。 青少年CGM使用者也继续证明A1c水平高于推荐目标，可能是由于 挑战与感知的CGM负担和相关的家庭功能有关。新颖的，以发展为目标的 在青春期早期提供的干预措施可以促进CGM的最佳吸收和使用，并减少 持续使用的心理社会障碍，但必须在关注健康的严格试点试验中进行评估 差距。目前的研究建议评估一种创新的行为干预，该干预利用经过认证的 糖尿病护理和教育专家(CDCES)传授解决问题和沟通技能 CGM数据和使用，针对青少年与父母与血糖数据相关的T1D交互，个性化CGM 挑战，以及每周一次青少年-家长联合审查CGM报告。干预还解决了HCP问题 通过互动教育了解糖尿病技术中的健康差距，并加强家庭支持 通过与同行家长顾问的联系。本研究旨在评价安慰剂的初步疗效。 行为干预，以提高CGM的使用和由此产生的T1D健康结果。60名青少年和他们的 父母将被招募参加这项试点随机试验，随机分配到立即干预 组或延迟干预组作为标准护理对照。干预内容将是 通过与青少年和家长的3次远程医疗会议提供，并通过与同龄人的联系提供支持 家长顾问。医疗和心理社会数据(包括A1c、CGM指标、CGM负担和福利、 糖尿病痛苦和与糖尿病相关的家庭冲突)将从青少年和父母那里收集，地址为 CGM启动后第一年的基线和三个随访时间点。我们将采用定量的 以及定性分析，以评估干预的可行性、可接受性和影响。增强CGM访问权限 在这个关键的发展关头使用，为量身定做的支持和问题提供了绝佳的机会- 解决，导致糖尿病自我管理的潜在持久改善。这项试点试验的结果将 直接通知多点随机临床试验以评估疗效，长期目标是确定 有效的行为策略，可以整合到常规的糖尿病教育和护理中。

PROJECT SUMMARY/ABSTRACT Young adolescents (ages 10-15) with type 1 diabetes (T1D) are at high risk for deterioration of glycemic control and relatedly poor overall T1D self-management. Continuous glucose monitors (CGM) provide real-time indicators of glucose levels and alert users to hypoglycemia and hyperglycemia. Consistent, informed use of CGM has the potential to improve glycemic control and related T1D health outcomes. However, adolescents with T1D are the least likely age group to utilize CGM and significant health disparities exist in access to and use of CGM among youth from racial and ethnic minority backgrounds and youth with public insurance. Adolescent CGM users also continue to evidence A1c levels above recommended targets, potentially due challenges related to perceived CGM burden and related family functioning. Novel, developmentally targeted interventions delivered early in adolescence could promote optimal uptake and use of CGM and reduce psychosocial barriers to sustained use but must be evaluated in rigorous pilot trials that attend to health disparities. The current study proposes to evaluate an innovative behavioral intervention that utilizes certified diabetes care and education specialists (CDCES) to teach problem-solving and communication skills around CGM data and use, targeting adolescent-parent T1D interactions related to glucose data, individualized CGM challenges, and weekly adolescent-parent joint review of CGM reports. The intervention also addresses HCP knowledge of health disparities in diabetes technology through interactive education, and boosts family support through connection with peer parent consultants. This study aims to evaluate the preliminary efficacy of the behavioral intervention to enhance CGM use and resulting T1D health outcomes. Sixty adolescents and their parents will be recruited for this pilot randomized trial, randomly assigned to either an immediate intervention group or a delayed intervention group serving as a standard care comparison. Intervention content will be delivered via 3 telemedicine sessions with adolescents and a parent and supported by connection with a peer parent consultant. Medical and psychosocial data (including A1c, CGM indicators, CGM burdens and benefits, diabetes distress, and diabetes-related family conflict) will be collected from adolescents and a parent at baseline and three follow-up time points across the first year after CGM initiation. We will employ quantitative and qualitative analyses to evaluate intervention feasibility, acceptability, and impact. Enhancing CGM access and use at this key developmental juncture provides an excellent opportunity for tailored support and problem- solving, resulting in potentially lasting improvement in diabetes self-management. Results of this pilot trial will directly inform a multi-site randomized clinical trial to evaluate efficacy, with the long term goal of identifying effective behavioral strategies that can be integrated into routine diabetes education and care.