Administrative Core

项目摘要-管理核心(AC) 印第安纳州阿尔茨海默病研究中心(IADRC)行政核心(AC)的作用是 为中心提供战略规划、管理、资源和监督，以支持其持续 任务。这一角色的重要性是基于美国AD国家计划(NAPA)，以预防和 通过病因学、早期发现和治疗方面的创新研究，到2025年有效治疗阿尔茨海默病。帮助 实现这些目标IADRC为IADRC续签申请提出了四个总体中心目标： (1)支持、加强和拓展针对发病机制的阿尔茨海默病及相关痴呆的创新研究， 诊断、治疗和预防；(2)提供关键研究资源和基础设施以支持 现有研究，并使新的创新研究成为可能，包括纵向跟踪的特点良好的研究 研究参与者队列；(3)大力支持地方、区域和国家/国际痴呆症 开展研究合作，以促进NIA、国家ADRC网络、国家适应行动方案和相关联邦机构的目标 优先事项；以及，(4)为各级学习者提供与发展与发展有关的教育和培训机会； 包括那些有着不同背景和需求的人。审计委员会负责全面管理和 IADRC的战略方向。在安德鲁博士的带领下，中心和AC内部的领导力一直很稳定 塞金自2013年以来一直担任中心主任。Brad Glazier长期担任IADRC署长和 萨拉·范·海登是新任研究运营经理。咨询委员会有六个具体目标：(1)总体目标 阿尔茨海默病及相关疾病研究的方向和战略规划。空调将有助于利用现有的 项目和教师的优势，并为科学发展和影响开发新的机会。它还将 促进各核心之间的融合，促进主题凝聚力。咨询委员会将协调执行委员会， 包括主要领导，为中心目标的实现提供建议和帮助。(二)提供行政支持， 资源管理和监督职能。(3)确保对科学的持续评价和监督 进步、研究和培训。(4)推进机构间发展研究委员会促进和扩大创新研究的目标， 与AD/ADRD相关的培训和合作学术活动。(5)发展和管理IADRC 发展项目方案，包括征求建议书、强有力和不偏不倚的审查程序、 和基于外部资金和出版物的跟踪结果指标；和(6)作为有效的 与重要的外部组织建立联系，并促进与其他区域、国家和 国际AD研究计划。这包括与NIA以及NACC、NCRAD、 ADNI、DIAN、Leads、ACTC、ADGC/ADSP、AMP-AD、ADMC/ADMP、Model-AD、Treat-AD和其他 财团。美洲发展研究中心致力于实现这些目标，以支持和加快在以下方面的进展 应对阿尔茨海默病和相关疾病的挑战。

Project Summary – Administrative Core (AC) The role of the Administrative Core (AC) of the Indiana Alzheimer Disease Research Center (IADRC) is to provide strategic planning, management, resources, and oversight for the Center in support of its continued mission. The significance of this role is based on the U.S. National Plan for AD (NAPA), to prevent and effectively treat AD by 2025 through innovative research on etiology, early detection, and therapeutics. To help accomplish these goals the IADRC has proposed four Overall center aims for the IADRC renewal application: (1) Support, enhance, and expand innovative research on AD and related dementias targeting pathogenesis, diagnosis, treatment, and prevention; (2) Provide critical research resources and infrastructure to support existing studies and enable new innovative research, including a well-characterized longitudinally followed cohort of research participants; (3) Strongly support local, regional, and national/international dementia research collaborations to further the goals of the NIA, national ADRC Network, NAPA and related federal priorities; and, (4) Provide educational and training opportunities related to ADRD for learners of all levels, including those with diverse backgrounds and needs. The AC is responsible for overall management and strategic direction of the IADRC. Leadership within the Center and AC has been stable, with Dr. Andrew Saykin serving as the Center Director since 2013. Brad Glazier has long served as IADRC Administrator and Sarah Van Heiden is the new Research Operations Manager. The AC has six specific aims: (1) Overall direction and strategic planning for research on AD and related disorders. The AC will help to leverage existing strengths of programs and faculty and develop new opportunities for scientific growth and impact. It will also foster integration among the cores for thematic cohesion. The AC will coordinate the Executive Committee, including key leaders to advise and help implement the Center goals. (2) Provide administrative support, resource management and oversight functions. (3) Ensure ongoing evaluation and oversight of scientific progress, research and training. (4) Advance the IADRC goals of fostering and expanding innovative research, training and collaborative academic activities related to AD/ADRD. (5) Develop and manage the IADRC Developmental Projects Program, including solicitation of proposals, a robust and impartial review process, and tracking outcome metrics based on external funding and publication; and (6) Serving as an effective interface to important external organizations and promoting collaboration with other regional, national and international AD research initiatives. This includes interaction with the NIA as well as the NACC, NCRAD, ADNI, DIAN, LEADS, ACTC, ADGC/ADSP, AMP-AD, ADMC/ADMP, MODEL-AD, TREAT-AD and other consortia. The IADRC is committed to accomplishing these aims to support and accelerate progress in addressing the challenges of AD and related disorders.