Administrative Core

作为对RFA-CA-20-001的回应，我们将创造美国-东非艾滋病毒相关恶性肿瘤 职业发展和预防、早期发现和治疗研究中心 高效联动治疗病毒相关癌症。RFA要求形成一个协作的 一个或多个美国机构与至少两个LMIC机构之间的伙伴关系。IT挑战 申请者进行相关研究，同时建设长期的生物医学研究能力 职业发展机会。我们将创建一个双重用途的多国网络来进行 研究以及赞助职业发展活动，仿照NIH机构K奖 计划，这是美国初级调查人员的一种成功方法。管理……的复杂性 要开展必要的活动，就需要一个精明而高效的中央行政机构。最重要的是 该机构的目标将是提供有效的科学领导和行政协调。 因此，行政核心的具体目标将是： 目标1.促进USEAHAMRC成员之间的内部沟通和协调 和活动。 目标2.领导与当地利益相关者、资助者和其他NCI U54的外部互动 财团成员。 目标3.为本组织的研究和职业发展目标提供财务监督 USEAHAMRC。 目标4.召集和协助外部咨询小组 核心将安排定期沟通，建立严格的文件组织结构， 设计自动化监测，并促进所有调查人员之间的科学交流(目标1)。我们 将与非洲卫生部、NCI和其他HAMRC的政策制定者接触，这些中心由 RFA(目标2)。此外，核心将评价季度财务报告，以确保负责任和 透明使用货币资源(目标3)。汇聚了各种积极参与和受影响的 社区成员、科学专家和政策官员，核心将汇集外部咨询 专家小组将帮助USEAHAMRC选择最相关的研究问题，参与 并就研究成果的适当传播提供咨询意见(目标4)。在结束时， 在资助期内，USEAHAMRC将满足RFA的要求并处于有利地位 以实现下一阶段的研究和能力建设目标。行政核心将拥有 优化其财务资源的使用，同时作为我们新兴非洲委托人的典范 调查人员在建立领导力和行政研究技能时可以效仿。

In response to RFA-CA-20-001, we will create the United States-East Africa HIV-Associated Malignancy Research Center (USEAHAMRC) for Career Development and the Prevention, Early Detection and Efficient Linkage to Care for Virus-related Cancers. The RFA requires formation of a collaborative partnership between one or more US institution and institutions in at least two LMICs. It challenges applicants to conduct relevant research while also building long-term biomedical research capacity and career development opportunities. We will create a dual purpose multi-country network to conduct research as well as to sponsor career development activities modeled after the NIH institutional K award program, a successful approach for junior investigators in the US. To manage the complexity of required activities, an astute and efficient central administrative body is needed. The overarching objective of this body will be to provide effective scientific leadership and administrative coordination. Accordingly, the specific aims of the Administrative Core will be to: Aim 1. Facilitate internal communication and coordination between USEAHAMRC members and activities. Aim 2. Lead efforts in external interactions with local stakeholders, funders, and other NCI U54 consortium members. Aim 3. Provide financial oversight for the research and career development objectives of the USEAHAMRC. Aim 4. Convene and facilitate the External Advisory Panel The Core will schedule regular communications, establish rigorous document organization structures, design automated monitoring, and stimulate scientific exchange amongst all investigators (Aim 1). We will engage policy makers at African Ministries of Health, the NCI, and other HAMRCs funded by the RFA (Aim 2). In addition, the Core will evaluate quarterly financial reports to ensure responsible and transparent use of monetary resources (Aim 3). Bringing together a variety of engaged and affected community members, scientific experts, and policy officials, the Core will assemble an External Advisory Panel, which will assist the USEAHAMRC with choosing the most relevant research questions, engage the community, and advise on appropriate dissemination of research findings (Aim 4). At the end of the funding period, the USEAHAMRC will have fulfilled the requirements of the RFA and be well positioned to pursue the next phase of research and capacity-building goals. The Administrative Core will have optimized usage of its financial resources while serving as a model for our emerging African principal investigators to emulate as they build leadership and administrative research skills.