Phages Helping Acquire Genuine Experiences in Science (PHAGES)

拟议的项目要求在五年内提供135万美元，以建立 在蒙大拿理工大学成功实施的“噬菌体挖掘”计划我们的目标是：1）使教师具备 知识，技能和处置，以提供高质量的噬菌体为基础的 学生的研究机会; 2）建立一个可持续的管道， 学生进入科学; 3）创建自我维持的卫星实验室，以确保 服务不足地区的学生有机会在当地进行研究。选择 在课堂上参与噬菌体发现4年或更长时间的教师领导者 年将担任同侪导师，以扩大该项目的同事的教室。 1)K-12学生，教师和本科生的多样化人口将 参与发现和表征噬菌体的研究工作。拟建项目 将整合K-12外展计划，以扩大参与教师的骨干队伍， 为成千上万的K-12学生提供真正的研究经验，并严格衡量 该计划的影响。我们假设这种定制的交付和个性化 辅导将提高新参与教师的保留率，增加教师的多样性， 参与的学生，并扩大该计划的地理范围。 2)在SEPA和INBRE计划之间的最前沿合作中，我们目前正在 试行一项计划，以拓宽大学预科本科研究人员的渠道。的学生 参与噬菌体发现获得夏季和学年研究的支持。这 管道将在PHAGES项目期间扩大。在完成高中研究后 项目，这些新的大学生将过渡到蒙大拿州的INBRE-supported项目在任何 蒙大拿州八个INBRE参与机构，深化他们的研究经验， 增加蒙大拿州学生进入生物医学研究的渠道。 3)在PHAGES的支持下，每位教师都将发展知识，技能， 基础设施，以最适合他或她的形式提供课堂噬菌体发现 学区，包括建立卫星实验室， 材料和交付方案。项目成果和编写的材料将 通过出版物、互联网以及在地方、区域和国际各级 国家科学和科学教育会议。因为有>100所大学和学院 教师参与噬菌体发现在大学课堂上，这个计划可以提供一个 该模型将HHMI SEA-PHAGES计划的范围扩大到K-12教师和学生。

The proposed project requests $1.35 million over five years to build sustainability for the successful “Phagedigging” program at Montana Tech. We aim to 1) equip teachers with the knowledge, skills, and dispositions to provide high-quality bacteriophage-based research opportunities for students; 2) establish a sustainable pipeline for students into the sciences; and 3) create self-sustaining satellite labs to ensure that students in underserved areas have access to local research opportunities. Select teacher leaders who have been involved with phage discovery in their classrooms for 4 or more years will serve as peer mentors to expand the project to their colleagues' classrooms. 1) A diverse population of K-12 students, teachers, and undergraduate students will participate in research efforts to discover and characterize bacteriophages. The proposed project will integrate K-12 outreach programs to broaden the cadre of participating teachers and provide thousands of K-12 students with genuine research experiences and rigorously measure the effects of the program. We hypothesize that this customized delivery and personalized mentoring will enhance retention of newly participating teachers, increase the diversity of participating students, and expand the geographical reach of the program. 2) In a forefront collaboration between SEPA and INBRE programs, we are currently piloting a program to widen the pipeline of precollege undergraduate researchers. Students who participated in phage discovery receive support for summer and academic year research. This pipeline will expand during the PHAGES project. After completing high school research projects, these new college students will transition to Montana INBRE-supported projects at any of eight Montana INBRE participating institutions, deepening their research experiences, and increasing the pipeline of Montana students into biomedical research. 3) With support from PHAGES, each teacher will develop the knowledge, skills, and infrastructure to provide classroom phage discovery in formats most appropriate for his or her school district, including the establishment of satellite labs for independent preparation of materials and delivery of the program. The project results and materials developed will be widely disseminated through publications, internet, and presentations at local, regional, and national science, and science education conferences. As there is >100 universities and college faculty participating in phage discovery in college classrooms, this program may provide a model to expand the reach of the HHMI SEA-PHAGES program to K-12 teachers and students.