Administrative Core

项目摘要/摘要--行政核心 管理核心(核心A)的目的是支持加州大学洛杉矶分校的翻译目标 孢子在脑癌中起着组织中枢的作用。核心负责监督和 孢子的日常功能，并提供组织、行政和科学领导(两者 基本的和临床的)孢子的所有方面，包括所有 调查人员和委员会成员。它将提供科学管理，包括持续监督和 对所有项目和核心进行科学审查，以确保达到规定的孢子科学目标。 核心对预算的全面财务管理和适当的归档负有最终责任 预算信息。它将定期组织会议和研讨会，并提供 孢子研究人员承诺参加NCI脑孢子冬至和其他年度务虚会 与NCI相关的会议/讲习班和活动。一年一度的加州大学洛杉矶分校的计划和组织 脑癌孢子研讨会，包括外部咨询委员会(EAB)的参与，将是 行政核心的责任。这个核心将监督孢子的管理 发展研究(DRP)和职业提升计划(CEP)，同时提供监督和 确保遵守所有UCLA、NCI和联邦法规和要求，包括维护 适当的动物和人类受试者批准和监测所有已制定的政策 将妇女和代表性不足的少数群体包括在内。它将是孢子和NCI之间的联络人- 被指定为琼森综合癌症中心，其他加州大学洛杉矶分校的学术和行政机构， NIH/NCI工作人员、IAB/EAB成员和患者倡导团体。行政核心还将确保 适当地共享数据和资源，以促进孢子内和孢子间的合作， 通过新的加州大学洛杉矶分校脑孢子数据提供集成和集中的数据管理支持 管理(Brain-SPOD)平台，维护/更新加州大学洛杉矶分校脑孢子内联网和网站。 管理核心由Linda M.Liau领导，医学博士，博士，MDA，孢子首席研究员，谁 监督加州大学洛杉矶分校所有的脑癌孢子活动。

PROJECT SUMMARY/ABSTRACT – Administrative Core The purpose of the Administrative Core (Core A) is to support the translational objectives of the UCLA SPORE in Brain Cancer by serving as its organizational hub. The Core is responsible for the oversight and daily functions of the SPORE and provides organizational, administrative, and scientific leadership (both basic and clinical) for all of the aspects of the SPORE, including coordination and communication between all investigators and committee members. It will provide scientific management, including ongoing oversight and scientific review of all projects and cores to ensure that the stated scientific goals of the SPORE are met. The Core has ultimate responsibility for the overall financial management of the budget and appropriate filing of budgetary information. It will organize regularly scheduled meetings and seminars, and provide commitment of SPORE investigators to attend the annual NCI Brain SPORE Mid-Winter Retreat and other relevant NCI-related meetings/workshops and activities. The scheduling and organization of an annual UCLA Brain Cancer SPORE Symposium, including participation of the External Advisory Board (EAB), will be the responsibility of the Administrative Core. This Core will oversee the administration of the SPORE Developmental Research (DRP) and Career Enhancement Programs (CEP), while providing oversight and assuring compliance with all UCLA, NCI, and Federal regulations and requirements, including maintenance of appropriate animal and human subject approvals and monitoring of all the established policies for the inclusion of women and underrepresented minorities. It will be the liaison between the SPORE and the NCI- designated Jonsson Comprehensive Cancer Center, other UCLA academic and administrative bodies, NIH/NCI staff, IAB/EAB members, and patient advocacy groups. The Administrative Core will also ensure that data and resources are shared appropriately in order to promote intra- and inter-SPORE collaboration, provide integrated and centralized data management support through a new UCLA Brain SPORE Data Management (Brain-SPOD) platform, and maintain/update the UCLA Brain SPORE intranet and website. The Administrative Core is led by Linda M. Liau, MD, PhD, MDA, the SPORE principal investigator, who oversees all UCLA Brain Cancer SPORE activities.