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中文摘要
翻译
国家过敏和传染病研究所(NIAID)、国家卫生研究院(NIH)的艾滋病司的任务是增加对人类免疫缺陷病毒(HIV)的发病和传播的基本知识,支持艾滋病毒感染及其并发症的治疗方法的开发,并支持疫苗和其他预防战略的开发。可靠的实验室数据对于候选艾滋病毒疫苗平台和免疫原的临床评估至关重要。为支持单一或多个候选疫苗试验而进行化验的多个实验室的数据必须准确和可重复性。外部质量保证计划监督实验室(EQAPOL)的目的是让人们相信,各个实验室能够产生可靠的数据,以支持艾滋病毒疫苗免疫原的进步。EQAPOL通过参与验证分析的开发和可用性来支持这些努力,提供通用的和特征良好的试剂和标准操作程序(SOP),并提供外部质量保证(EQA)计划来衡量和监控实验室性能。
英文摘要
The mission of the Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), is to increase basic knowledge of the pathogenesis and transmission of the human immunodeficiency virus (HIV), support the development of therapies for HIV infection and its complications, and support the development of vaccines and other prevention strategies. Reliable laboratory data are essential to the clinical evaluation of candidate HIV vaccine platforms and immunogens. Data from multiple laboratories performing assays in support of single or multiple vaccine candidate trials must be accurate and reproducible. The purpose of the External Quality Assurance Program Oversight Laboratory (EQAPOL) is to provide confidence that individual laboratories generate reliable data to support HIV vaccine immunogen advancement. EQAPOL supports these efforts by participating in the development and availability of validated assays, providing common and well-characterized reagents and Standard Operating Procedures (SOPs), and providing External Quality Assurance (EQA) programs to measure and monitor laboratory performance.
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IMMUNOLOGY QUALITY ASSESSMENT (IQA) PROGRAM
  • 批准号:
    10896891
  • 项目类别:
  • 资助金额:
    $182.57万
  • 财政年份:
    2023
  • 负责人:
    THOMAS DENNY
  • 依托单位:
NIAID VIROLOGY QUALITY ASSURANCE (VQA)
  • 批准号:
    10868384
  • 项目类别:
  • 资助金额:
    $400.91万
  • 财政年份:
    2023
  • 负责人:
    THOMAS DENNY
  • 依托单位:
COVID-19: External Quality Assurance Program Oversight Laboratory (EQAPOL)
  • 批准号:
    10930677
  • 项目类别:
  • 资助金额:
    $183.02万
  • 财政年份:
    2023
  • 负责人:
    THOMAS DENNY
  • 依托单位:
External Quality Assurance Program Oversight Laboratory (EQAPOL)
  • 批准号:
    10930676
  • 项目类别:
  • 资助金额:
    $503.68万
  • 财政年份:
    2023
  • 负责人:
    THOMAS DENNY
  • 依托单位:
海外基金