Computer Core

摘要/摘要 计算机核心的作用是为整个视觉科学家提供专门的计算机服务 哥伦比亚大学，优先考虑由NEI RO1拨款支持的调查人员。计算机技术是 对所有现代视觉科学至关重要：数据库管理、遗传和神经科学计算、可靠 数据存储，并作为实验室仪器的在线附件，而核心促进了所有这些 流程。核心有两个主要组成部分：1)哈克内斯眼科研究所(HEI)网站，其中包括：a. 基因组分析套件，B.数据库和服务器中心，C.计算和编程服务；以及 2)Zuckerman Mind，Brain，and Behavior Institute(ZMBBI)，核心提供实时软件和 视觉系统神经科学的硬件组件。 尽管该大学提供标准的PC备份(例如对Windows和Microsoft Office的支持)， 视觉系统神经科学需要更复杂的支持。在系统神经科学方面，而不是 执行孤立的数据分析功能，将计算机集成到实验装置本身中， 实时执行一系列功能，例如控制动物的行为、测量眼睛 运动和手臂运动，收集单个神经元的活动，并进行初步的数据分析。这 需要特殊的实时操作系统，通常超出大学PC技术人员的能力范围，以及 特殊接口，使实验仪器和计算机之间有一个有效的接口。 由于Zuckerman Institute现在提供服务器和异地备份设施，因此将Core腾出用于 更有创意的计算机界面开发，例如方便新开发的多个单 神经元记录，包括使高速图形卡适应生理记录，在其他领域 ZMBBI计算机团队的专业知识。核心还将提供紧急计算机备份，当 ZMBBI团队不可用。 哈克尼斯眼科研究所严重依赖于SQL数据库和编程，这也是一种能力 除了大学里的计算机技术员。高等学校计算机核心的新组件是 创新的基因组学分析套件，将提供集成的数据管理和分析能力 用于基因和成像数据。核心还将促进视觉系统组之间的合作 研究人员本身，以及实验视觉科学家和计算神经科学家之间的合作， ZMBBI的理论神经科学中心。在Hei，它将支持以下几个方面的协作 视觉科学家和视觉研究的新手。

Summary/Abstract The role of the Computer Core is to provide specialized computer services to vision scientists throughout Columbia University, with priority given to investigators supported by NEI RO1 grants. Computer technology is critical to all modern visual science: database management, genetic and neuroscientific computation, reliable data storage, and serving as on-line adjuncts to laboratory instruments, and the Core facilitates all of these processes. The Core has 2 major components: 1) the Harkness Eye Institute (HEI) site, which includes: A. The Genomics Analysis Suite, B. The databases and server center, C. Computing and programming services; and 2) the Zuckerman Mind, Brain, and Behavior Institute (ZMBBI), where the Core provides real-time software and hardware components for visual systems neuroscience. Although the University provides standard PC backup (e.g. support for Windows and Microsoft Office), visual systems neuroscience requires much more sophisticated support. In systems neuroscience rather than performing an isolated data analysis function, computers are integrated into the experimental apparatus itself, performing a number of functions in real time, such as controlling the animal’s behavior, measuring eye movement and arm movement, collecting single neuron activity, and doing preliminary data analysis. This requires special real-time operating systems, usually beyond the ability of the University PC technicians, and special interfaces to enable an efficient interface between the experimental apparatus and the computer. Because the Zuckerman Institute now provides server and off-site backup facilities, this frees up the Core for more creative computer interface development, for example to facilitate the new development of multiple single neuron recording, including the adaptation of high speed graphics cards to physiological recording, areas beyond the expertise of the ZMBBI computer team. The Core will also provide emergency computer backup when the ZMBBI team is unavailable. The Harkness Eye Institute is heavily reliant on SQL databases and programming, again a capability beyond that of the University computer technicians. The new component of the Computer core at the HEI is the innovative Genomics Analysis Suite, which will provide integrated data management and analysis capabilities for genetic and imaging data. The Core will also foster collaborations among the group of visual systems investigators themselves, and also between experimental vision scientists and computational neuroscientists at the ZMBBI’s Center for Theoretical Neuroscience. At HEI it will enable a number of collaborations between vision scientists and scientists new to vision research.