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中文摘要
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项目摘要 集体行为是在所有生命王国中自发产生的社会和协调过程。 它们可以在不同的背景下被观察到:萤火虫的眨眼,蝗虫大军的行进, 鱼类的鱼群,社会细菌的聚集,以及病毒攻击。他们甚至在运动中被观察到 无生命的物体,例如机器人群。集体行为发生在生活系统的所有尺度上; 同步行为从有机体延伸到组织、细胞和分子。具有讽刺意味的是,研究 在集体行为上不协调。不同的科学小组致力于研究这些现象,在许多 学科,包括进化生物学、微生物学、数学、物理学和工程学。尽管 正在处理的问题有令人兴奋的重叠,群体之间的互动一直很稀少。我们提出三个建议 创建一个致力于集体行为研究的统一和持久的研究社区的步骤 提供跨学科的桥梁:(1)建立集体行为研究的跨学科社区 通过每年举办两次关于集体行为的戈登研究会议(GRC),(2)建立一个持久的 基于此GRC的跨学科包容性集体行为研究社区,通过招募 来自代表人数不足的群体的参与者;以及3)为集体问题GRC设立一个永久地点 行为。为了开始这一社区建设并促进这一新的跨学科领域,我们将举办第一届 关于集体行为的GRC于2023年8月13日至18日在缅因州纽里市周日河的Grand Summit酒店举行。 本次会议的目标是在科学家之间建立跨学科的合作,以分享 信息、方法和技术的协调努力,以转变对集体调查的 行为。具体地说,我们期待这次会议将促进发现跨尺度的统一原则。 和生物体,并揭示这些发现,无论是实验上的还是理论上的,都可以在未来使用 实验、计算、机器人学和医学应用。此外,这次会议将有助于进一步 我们对集体行为如何从单个组件的行为中产生的理解,例如 个体、细胞或分子。 65%的受邀演讲者和讨论负责人(最有可能的是与会者)将他们的 对NIBIB优先考虑的领域进行研究。这包括使用合成和计算生物学以及 数学建模和模拟,用于分析有生命和无生命系统中的集体行为。 这一新兴研究领域的研究人员将成为NIBIB新调查人员的丰富来源。此外, NIBIB资金将补充旅行和注册费用,预计将增加 女性,URM博士后研究员和研究生,以及早期职业调查人员,否则他们可以 不能参加这次会议。我们特别感兴趣的是支持这群年轻和多样化的 研究人员,因为他们将推动集体行为这一新研究领域的未来。
英文摘要
Project Summary Collective behaviors are social and coordinated processes that arise spontaneously in all kingdoms of life. They can be observed in a variety of contexts: the blinking of fireflies, the marching of an army of locusts, the schooling of fish, the aggregation of social bacteria, and viral attacks. They are even observed in the movement of inanimate objects, such as robot swarms. Collective behaviors occur on all scales of living systems; synchronous behaviors extend from the organism to the tissue, to the cell, to the molecule. Ironically, research on collective behaviors is not coordinated. Disparate scientific groups work on these phenomena in many disciplines, including evolutionary biology, microbiology, mathematics, physics, and engineering. Although the problems being pursued have exciting overlaps, interaction between groups has been sparse. We propose three steps to create a unified and enduring research community committed to the study of collective behavior by providing trans-disciplinary bridges: (1) build a trans-disciplinary community of collective behavior researchers by holding a biannual Gordon Research Conference (GRC) on Collective Behavior, (2) build an enduring inclusive trans-disciplinary community of collective behavior researchers based around this GRC by recruiting participants from under-represented groups; and 3) establish a permanent venue for the GRC on Collective Behavior. To begin this community building and to promote this new inter-disciplinary field, we will hold the first GRC on Collective Behavior August 13 - 18, 2023 at Grand Summit Hotel at Sunday River, Newry, ME. The goal of this conference is to establish trans-disciplinary collaborations between scientists to share information, approaches, and technologies in a coordinated effort to transform investigations of collective behavior. Specifically, we expect the conference will promote the discovery of unifying principles across scales and organisms and uncover how the findings, both experimental and theoretical, can be used in future experimentation, computation, robotics, and medical applications. Moreover, the conference will help to further our understanding of how collective behaviors emerge from the behavior of single components, such as individuals, cells or molecules. Sixty-five percent of the invited speakers and discussion leaders (and most likely the attendees) focus their research on areas that are a high priority for NIBIB. This includes using synthetic and computational biology and mathematical modeling and simulations to analyze collective behaviors in both animate and inanimate systems. The researchers in this emerging field of study would be a rich source of new NIBIB investigators. Furthermore, NIBIB funding, which will supplement travel and registrations costs, is expected to increase the participation of women, URM postdoctoral fellows and graduate students, and early career investigators, who otherwise could not afford to attend this conference. We are especially interested in supporting this group of young and diverse researchers, as they will fuel the future of this new research area of collective behavior.
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会议论文
The Role of Biofilm on Margin Stability and the Development of Secondary Caries
  • 批准号:
    8990685
  • 项目类别:
  • 资助金额:
    $35.08万
  • 财政年份:
    2014
  • 负责人:
    HEIDI B KAPLAN
  • 依托单位:
TRANSDUCTION OF THE A SIGNAL IN MYXOCOCCUS DEVELOPMENT
TRANSDUCTION OF THE A SIGNAL IN MYXOCOCCUS DEVELOPMENT
TRANSDUCTION OF THE A SIGNAL IN MYXOCOCCUS DEVELOPMENT
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: