Khulani Siphile Siphuhle Training Program in South Africa (KiSS-TP)

项目摘要/摘要 南非是全球艾滋病毒流行的中心，其绝对数最多 世界上任何国家的艾滋病毒携带者(约790万人)。南非也是世界上结核病患病率最高的国家(852 每100,000名15岁人口中)，合并结核病的发病率最高的是与 爱滋病毒。艾滋病毒和结核病的高发病率由于常见精神障碍的高负担而进一步加剧 (慢性MDS)，特别是在与艾滋病毒和艾滋病毒/结核病并存时。这些全国性的健康趋势背后是 种族主义种族隔离政权遗留下来的省和地区健康不平等现象。结构性的 种族隔离造成的不平等继续影响着社会、经济和文化权利的分布和普遍 影响健康结果的行为风险因素，所有这些因素继续在国家调查中观察到 和健康指标。 类似于美国历史上的黑人学院和大学，南非历史上的 弱势机构(HDI)是在种族隔离时期建立的非白人隔离机构。到期 对于历史上的不公正，人类发展机构没有产生类型的学术资源或研究基础设施来 使他们能够与富裕的同行竞争，或在研究中建立全球足迹 环境。 为了解决南非种族主义种族隔离政权造成的这些历史性的健康和体制不平等问题， 投资于德班、约翰内斯堡或开普敦等历史优势城市以外的机构，以及 在南非东开普省的人类发展倡议中创造一大批尖端艾滋病毒研究人员， 我们提出了Khulani Siphile Siphuhle培训计划(KISS-TP)。具体地说，我们将提供一个密集的， 为8名精心挑选的硕士级教职员工提供跨学科、有指导的博士培训计划 黑尔堡大学(UFH)、沃尔特西苏鲁大学(WSU)和德斯蒙德·图图健康基金会(DTHF) 东开普省的研究计划；UFH和WSU是南非八个指定的人类发展机构中的两个。我们还将 通过专业发展和进步加强东开普省博士培训能力 为密歇根州立大学和西澳州立大学的教职员工和D43学员提供的独立研究方案。我们的培训联盟将包括 DTHF、UFH、西澳州立大学、开普敦大学和加州大学全球卫生研究所。通过选择PHD 受训人员是东开普省人类发展机构和研究机构的初级教职员工和工作人员，我们确保 即时投资回报：1)东开普省尖端研究能力的增加，2) 支持UFH和WSU的新博士项目的学术能力，以及3)培训下一代艾滋病毒 研究人员。学员将有机会通过指导研究来练习他们的发展技能 东开普省重点关注南非区域四个关键需求领域之一：青少年健康， 艾滋病毒护理和预防；男子健康、艾滋病毒护理和预防；艾滋病毒和精神卫生；以及艾滋病毒和结核病。

PROJECT SUMMARY/ ABSTRACT South Africa is the centre of the global HIV epidemic and has the largest absolute number of people living with HIV (~7.9 million) of any country in the world. South Africa also has the world’s highest TB prevalence (852 per 100,000 population aged >15 years), and the greatest incidence of co-morbid TB among those living with HIV. These high rates of HIV and TB are further compounded by the high burden of common mental disorders (CMDs), especially when co-morbid with HIV and HIV/TB. Underlying these national-level health trends are provincial and district health inequalities resulting from the legacy of the racist apartheid regime. The structural inequities wrought by apartheid continue to influence the distribution and prevalence of social, economic and behavioural risk factors that impact health outcomes, all of which continue to be observed in national surveys and health indicators. Similar to Historically Black Colleges and Universities in the United States, South Africa’s Historically Disadvantaged Institutions (HDIs) were established as non-White, segregated institutions during apartheid. Due to historic injustices, HDIs have not generated the type of academic resources or research infrastructure to enable them to compete with their affluent counterparts or establish a global footprint within the research environment. To address these historic health and institutional inequities wrought by South Africa’s racist Apartheid regime, invest in institutions outside of the historically advantaged cities of Durban, Johannesburg or Cape Town, and create a critical mass of cutting-edge HIV researchers within the HDIs of South Africa’s Eastern Cape Province, we propose the Khulani Siphile Siphuhle Training Program (KiSS-TP). Specifically, we will offer an intensive, interdisciplinary, mentored PhD training program to eight carefully selected Masters-level faculty and staff at University of Fort Hare (UFH), Walter Sisulu University (WSU) and the Desmond Tutu Health Foundation’s (DTHF) research program in Eastern Cape; UFH and WSU are two of South Africa’s eight designated HDIs. We will also strengthen PhD training capacity in Eastern Cape through professional development and progression towards independent research programmes for UFH and WSU faculty and D43 trainees. Our training consortium will include DTHF, UFH, WSU, University of Cape Town and University of California Global Health Institute. By selecting PhD trainees who are junior faculty and staff affiliated with Eastern Cape HDIs and research institutions, we ensure an immediate return-on-investment regarding: 1) an increase in cutting-edge research capacity in Eastern Cape, 2) support of academic capacity for nascent PhD programs at UFH and WSU, and 3) training of next generation HIV researchers. Trainees will have the opportunity to practice their developing skills through mentored research in the Eastern Cape focused on one of four critical areas of need in that region of South Africa: Adolescent health, HIV care and prevention; Men’s health, HIV care and prevention; HIV and mental health; and HIV and TB.