Human Tissues Core
Human Tissues Core
批准号:
10688020
负责人:
Brian T Fife
金额:
$6.82万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-09-15 至 2024-08-31
关键词:
AccelerationAntigensAutoantigensAutoimmune DiseasesBasic ScienceCD4 Positive T LymphocytesCadaverCellsCollaborationsConsentCryopreservationDatabasesEnsureFingersFreezingFutureGenerationsGoalsHealth Insurance Portability and Accountability ActHealth Service AreaHomeostasisHumanImmuneImmunologicsImmunologyInstitutional Review BoardsLeadLiquid substanceLiving DonorsLymphoid TissueMusNitrogenOperative Surgical ProceduresOrgan ProcurementsPatientsPeripheralPeripheral Blood Mononuclear CellPhysiologicalPreparationProcessProtocols documentationRecoveryRegulationResearchResearch PersonnelResourcesRiskSamplingSecureSerumServicesSpleenSurgeonSuspensionsT-LymphocyteTissue DonorsTissue SampleTissuesTonsilTranslational ResearchTranslationsVisionWritingcell bankcell preparationclinically relevantcost effectiveexperimental studyhuman tissueisletlymph nodesprogramstargeted treatmenttissue preparationtype I diabetic
中文摘要
摘要
人体组织核心的目标是提供具有成本效益的专家支持和服务,以加速
P01核心用户的人体免疫学研究。这一核心将促进机构审查委员会(IRB)
批准、收集、加工和分发新鲜的人体脾、淋巴结和扁桃体组织样本,用于
P01项目。该中心还将收集PBMC制剂中的血清,冷冻未使用的细胞,并促进
从冷冻库中回收单细胞。重要的是,P01核心用户收到的组织将被去识别
核心将维护一个未确认身份的患者样本数据库。人类组织核心C将利用
UMN的现有资源和专业知识,包括与临床医生和外科医生的持续合作
精简和扩展服务,为P01项目提供新鲜的人体免疫组织。
英文摘要
Summary
The goal of the Human Tissues Core is to provide expert cost-effective support and services to accelerate
human immunology research for P01 core users. This core will facilitate Institutional Review Board (IRB)
approval, collect, process and distribute fresh human tissue samples of spleen, lymph nodes, and tonsils for
P01 projects. The core will also collect serum from PBMC preparations, freeze unused cells, and facilitate
single cell recovery from cryostorage. Importantly, the tissue received by P01 core users will be de-identified
and the core will maintain a de-identified patient sample database. The Human Tissues Core C will leverage
existing resources and expertise at UMN, including ongoing collaborations with clinicians and surgeons to
streamline and expand services to provide fresh human immune tissue to the P01 projects.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Identifying and preventing antigen specific T cells in diabetes
-
批准号:10436364
-
项目类别:
-
资助金额:$59.03万
-
财政年份:2021
-
负责人:Brian T Fife
-
依托单位:
Identifying and preventing antigen specific T cells in diabetes
-
批准号:10634700
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项目类别:
-
资助金额:$59.03万
-
财政年份:2021
-
负责人:Brian T Fife
-
依托单位:
Identifying and preventing antigen specific T cells in diabetes
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批准号:10296946
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项目类别:
-
资助金额:$59.0万
-
财政年份:2021
-
负责人:Brian T Fife
-
依托单位:
Engineering CAR Tregs for type 1 diabetes
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批准号:10495238
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项目类别:
-
资助金额:$23.15万
-
财政年份:2021
-
负责人:Brian T Fife
-
依托单位:
Engineering CAR Tregs for type 1 diabetes
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批准号:10354415
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项目类别:
-
资助金额:$19.28万
-
财政年份:2021
-
负责人:Brian T Fife
-
依托单位:
Multiplex immune analysis of antigen specific CD4+ T cells in autoimmune diabetes
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批准号:9091431
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项目类别:
-
资助金额:$68.46万
-
财政年份:2015
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负责人:Brian T Fife
-
依托单位:
Multiplex immune analysis of antigen specific CD4+ T cells in autoimmune diabetes
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批准号:9271151
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项目类别:
-
资助金额:$40.0万
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财政年份:2015
-
负责人:Brian T Fife
-
依托单位:
Multiplex immune analysis of antigen specific CD4+ T cells in autoimmune diabetes
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批准号:8932879
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项目类别:
-
资助金额:$40.0万
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财政年份:2015
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负责人:Brian T Fife
-
依托单位:
Mechanisms of immune tolerance in autoimmune diabetes
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批准号:8786472
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项目类别:
-
资助金额:$37.14万
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财政年份:2013
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负责人:Brian T Fife
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依托单位:
Mechanisms of immune tolerance in autoimmune diabetes
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批准号:8649238
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项目类别:
-
资助金额:$37.14万
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财政年份:2013
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负责人:Brian T Fife
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依托单位:
Mechanisms of immune tolerance in autoimmune diabetes
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批准号:9181377
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项目类别:
-
资助金额:$37.13万
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财政年份:2013
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负责人:Brian T Fife
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依托单位:
Immune tolerance in humanized translational models to cure diabetes
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批准号:8299897
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项目类别:
-
资助金额:$21.76万
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财政年份:2012
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负责人:Brian T Fife
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依托单位:
Immune tolerance in humanized translational models to cure diabetes
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批准号:8416929
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项目类别:
-
资助金额:$17.95万
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财政年份:2012
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负责人:Brian T Fife
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依托单位:
Human Tissues Core
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批准号:10466851
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项目类别:
-
资助金额:$7.42万
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财政年份:1997
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负责人:Brian T Fife
-
依托单位:
Role of hybrid peptide specific T cells in diabetes
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批准号:10688008
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项目类别:
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资助金额:$35.95万
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财政年份:1997
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负责人:Brian T Fife
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依托单位:
Role of hybrid peptide specific T cells in diabetes
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批准号:10466845
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项目类别:
-
资助金额:$36.49万
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财政年份:1997
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负责人:Brian T Fife
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依托单位:
Autoimmune Mouse Core
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批准号:8592244
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项目类别:
-
资助金额:$13.79万
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财政年份:--
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负责人:Brian T Fife
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依托单位:
Autoimmune Mouse Core
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批准号:8841658
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项目类别:
-
资助金额:$13.52万
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财政年份:--
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负责人:Brian T Fife
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依托单位:
Autoimmune Mouse Core
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批准号:8662151
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项目类别:
-
资助金额:$13.79万
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财政年份:--
-
负责人:Brian T Fife
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依托单位:
Autoimmune Mouse Core
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批准号:9267922
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项目类别:
-
资助金额:$14.06万
-
财政年份:--
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负责人:Brian T Fife
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依托单位:
国内基金
海外基金
Neo-antigens暴露对肾移植术后体液性排斥反应的影响及其机制研究
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批准号:2022J011295
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项目类别:省市级项目
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资助金额:10.0万元
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批准年份:2022
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负责人:王亚伟
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依托单位:
结核分枝杆菌持续感染期抗原(latency antigens)的重组BCG疫苗研究
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批准号:30801055
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项目类别:青年科学基金项目
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资助金额:19.0万元
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批准年份:2008
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负责人:王丽梅
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依托单位: