The effect of e-cigarette and hookah use on the age of asthma onset in the USA

项目摘要 对现有行为数据的创新分析，以研究 过去30天的电子烟和水烟使用者中的哮喘发作对科学兴趣有反应 通过了解这些烟草产品的短期和长期影响， 这项建议的重点是青年和成人哮喘发作的年龄。电子烟和 水烟是目前烟草市场的主要特征，它们有可能 以类似香烟的方式危害使用者的健康。因此，估计哮喘发作的年龄 为了评估过去30天电子烟和水烟使用对从不吸烟者的影响， 最重要的是保护公众健康，教育公众，并为食品和药物管理局提供证据。 管理局（FDA）。关于哮喘发病年龄较早的信息将量化并显示 这些烟草产品的潜在风险，这可以帮助防止人们开始使用或激励 用户退出。此外，控制和治疗哮喘的最有效方法是早期发现哮喘。 这种疾病提供关于电子烟和水烟使用者哮喘发作年龄的信息， 帮助向医生和卫生保健提供者提供有关适当年龄的必要信息 为使用这些烟草产品的患者提供哮喘筛查窗口。我们建议估计 使用波1-5（以及在我们的研究期间释放的任何后续波 烟草与健康人口评估研究（PATH）提出了两个目标： 目的1：估计12-75岁以上青年和成人哮喘发作的年龄， 探索电子烟使用与哮喘发作年龄之间的关系， 其他风险因素。目的2：估计12-75岁以上青年和成人哮喘发作的年龄 年龄，并探讨水烟使用和哮喘发作后的年龄之间的关系， 控制其他风险因素。将在从不吸烟者中进行目标1和2的分析 使用者应避免香烟使用的潜在混淆。在以下方面的知识存在差距： 哮喘发作的年龄，特别是在电子烟和水烟使用者中。的最有效方法 建立这些联系需要纵向的、前瞻性的研究。很少有研究能证明 假设与烟草相关的健康结果的纵向数据，包括哮喘， 美国青年和成年人的全国代表。该项目满足了以下迫切需要： 了解并指导向FDA、烟草制品中心和一般 公众提供更多关于使用这些烟草产品的影响的信息，以减少他们的公众 美国的健康问题。

PROJECT SUMMARY Innovative analysis of existing behavioral data to study the etiology and epidemiology of the age of asthma onset among past 30-day e-cigarette and hookah users is responsive to the scientific interest area on health effects by understanding the short and long-term effects of these tobacco products in the U.S. This proposal focuses on the age of asthma onset in youth and adults. E-cigarettes and hookah are now dominant features of the current tobacco marketplace, and they have the potential to harm the health of users in ways similar to cigarettes. Therefore, estimating the age of asthma onset to evaluate the effect of past 30-day e-cigarette and hookah use among never cigarette users is paramount to protect public health, educate the public, and provide evidence to the Food and Drug Administration (FDA). Information on an earlier age of asthma onset will quantify and display the potential risk of these tobacco products, which can help prevent people from initiating use or motivate users to quit. In addition, the most effective way to control and treat asthma is with early detection of the disease. Providing information on the age of asthma onset in e-cigarette and hookah users can help provide necessary information to physicians and health care providers on the appropriate age windows for asthma screening in patients who use these tobacco products. We propose to estimate the age asthma of onset using waves 1-5 (and any subsequent waves released during our study period) of the Population Assessment of Tobacco and Health (PATH) Study. Two aims are proposed: Aim 1: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between e-cigarette use and the age of asthma onset after controlling for other risk factors. Aim 2: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between hookah use and the age of asthma onset after controlling for other risk factors. Analyses for Aims 1 and 2 will be conducted among never cigarette users to avoid potential confounding from cigarette use. There is a gap in the knowledge related to the age of asthma onset, specifically among e-cigarette and hookah users. The most effective way to establish these associations is with longitudinal, prospective research. Few studies can test hypotheses with longitudinal data on tobacco-related health outcomes, including asthma that is nationally representative of U.S. youth and adults. This project addresses a critical need to understand and guide efforts to provide FDA, the Center for Tobacco Products, and the general public with more information on the effects of using these tobacco products to reduce their public health toll in the United States.