Ultra-Fast Dose Rate (FLASH) Radiation Detector and Safety System
Ultra-Fast Dose Rate (FLASH) Radiation Detector and Safety System
批准号:
10714550
负责人:
RAYMOND BOISSEAU
金额:
$39.79万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
已结题
起止时间:
2022-09-16 至 2023-06-15
关键词:
AnimalsClinicalDependenceDevelopmentDoseDose-RateEngineeringEnvironmentFeedbackFutureGoalsInvestigationNormal tissue morphologyPatternPhasePolychlorinated BiphenylsProtonsRadiation therapyReportingResearchSafetyScanningStructureSuggestionSystemTechnologyTest ResultTestingTimeTo specifyToxic effectbasedensitydesigndetectordosimetryinterestionizationnovelproton beamradiation detector
中文摘要
动物研究表明,外束放射治疗在超高剂量率(40GY/S)下可减少正常组织的毒性,这种情况被称为闪光。闪光效应与峰值剂量率和束流时间结构的关系正在深入研究中。已经提出了一个巨大的峰值剂量率范围,这导致了对一系列新的探测器技术的研究兴趣,这些技术并不通常用于临床剂量学。我们将专注于
一种具体、可行的配置,同时仍能容纳正在考虑的所有探测器。
英文摘要
Animal studies show that external-beam radiotherapy reduces normal tissue toxicities when delivered at ultra-high dose rates (>40 Gy/s), a condition referred to as FLASH. The dependence of the FLASH effect on peak dose rate and beam time structure is under intense investigation. An enormous range of peak dose rates has been proposed, leading to research interest in a range of novel detector technologies that are not generally used in clinical dosimetry. We will concentrate on
a specific, feasible configuration while still accommodating the full range of detectors under consideration.
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国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
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批准号:31070748
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项目类别:面上项目
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资助金额:34.0万元
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批准年份:2010
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负责人:Christine Nardini
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依托单位: