NIDDK Extramural Digital Pathology Repository System (HALO LINK)

近年来，新技术和数据处理能力已经消除了分子和组织病理学数据集整合的障碍。美国国家糖尿病、消化和肾脏疾病研究所的几个临床研究网络已经将数字病理学知识库（DPR）与数字全载玻片图像（WSI）结合起来，以支持临床研究中心经典诊断标准的标准化。一个发展中的调查路线是“挖掘”这些数字集，以确定与疾病相关的特征。特征检测和特征识别的计算机辅助图像分析是这种调查的关键组成部分。集中式NIDDK数字病理学知识库将作为一个在线知识库，以促进WSI的标准化存档，目标是为标准化、发现和验证研究工作提供受控访问。

In recent years, new technology and data processing capabilities have removed barriers to integration of molecular and histopathological data sets. Several clinical research networks across the National Institute of Diabetes, Digestive and Kidney Diseases extramural programs have put Digital Pathology Repositories (DPRs) into place with digital whole slide images (WSI) available to support standardization of classical diagnostic criteria across clinical sites. A developing line of investigation is the “mining” of these digital sets to identify features which correlate with disease. Computer assisted-image analysis for feature detection and feature recognition are key components of such investigation. The Centralized NIDDK Digital Pathology Repository will serve as an online repository to facilitate standardized archiving of WSI with the goal of providing controlled access for standardization, discovery and validation research efforts.