Mentored Training in Molecular Epidemiology of Chronic Kidney Disease in Diverse Populations

摘要 慢性肾脏疾病影响着七分之一的美国成年人，是导致死亡和残疾的主要原因。慢性 肾脏疾病对美国不同的人群有很大的影响，包括黑人、拉美裔/拉美裔和 美国印第安人。慢性肾脏病的流行病学及分子危险因素研究 迫切需要不同人群中的疾病来指导公共卫生预防和干预，并 为临床医生开发治疗工具，以有效地治疗这种疾病。此K26应用程序将支持 医学博士，公共卫生硕士Nora Franceschini的保护时间，指导来自代表不足的团体的初级调查人员 不同人群慢性肾脏疾病的分子流行病学研究。弗朗西斯基尼博士 是一名肾病学家和流行病学家，有20年的多学科研究经验 慢性肾脏疾病和指导研究生和早期调查人员，包括来自 代表不足的群体。Franceschini博士制定了强大的国家卫生研究院支持 北卡罗来纳大学慢性肾脏疾病研究项目专注于 人口。这项研究计划为学员提供了多种学习严谨研究技能的机会 慢性阻塞性肺疾病流行病学、分子流行病学和生物标志物研究进展 肾脏疾病。拟议的活动和增强的指导技能支持提高高质量的目标 为下一代科学家(包括URGs)在她体内进行慢性肾脏疾病研究提供指导 研究计划。

ABSTRACT Chronic kidney disease affects one in seven U.S. adults and is a leading cause of death and disability. Chronic kidney disease has a substantial impact on U.S. diverse populations, including Blacks, Hispanics/Latinos and American Indians. Research on the epidemiology and molecular risk factors contributing to chronic kidney disease in diverse populations is much needed to guide public health prevention and interventions, and to develop therapeutic tools for clinicians to effectively treat the disease. This K26 application will support protected time for Nora Franceschini, MD MPH, to mentor junior investigators from underrepresented groups in science on molecular epidemiology research of chronic kidney disease in diverse populations. Dr. Franceschini is a nephrologist and an epidemiologist with a 20-year experience conducting multidisciplinary studies in chronic kidney disease and mentoring graduate students and early-stage investigators, including those from underrepresented groups. Dr. Franceschini has developed a strong National Institutes of Health supported research program on chronic kidney disease at the University of North Carolina focused on diverse populations. This research program offers multiple opportunities for trainees to learn rigorous research skills in state-of-art approaches for research in the epidemiology, molecular epidemiology and biomarkers of chronic kidney disease. Proposed activities and enhanced mentoring skills support the goals to increase high-quality mentoring for the next generation of scientists (including URGs) in chronic kidney disease research within her research program.