1/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries

项目总结 该项目实现了祖传人口网络(APN；PAR-20-026和PAR-20- 027)，即促进亚太国家联盟成员之间的计量和数据分析协调工作，以加强 严密性和可重复性，并为网络成员和科学界提供资源。通过一个 APN成员的共识过程、快感缺乏、认知、强迫症状、 自杀和歧视/耻辱被选为正在进行的研究的协调对象。这些 统一的衡量标准将在大约27,500名代表亚洲、拉丁语的个人中收集 美洲人和非洲人的祖先横跨15个国家。

PROJECT SUMMARY This project actualizes a primary goal of the Ancestral Populations Network (APN; PAR-20-026 and PAR-20- 027), namely to facilitate measurement and data analytic harmonization efforts across APN members to enhance rigor and reproducibility and generate a resource for network members and the scientific community. Through a consensus process of APN members, measures of anhedonia, cognition, obsessive-compulsive symptoms, suicidality, and discrimination/stigma were selected for harmonization across ongoing studies. These harmonized measures will be collected across an estimated 27,500 individuals representing Asian, Latin American, and African ancestries spanning over 15 countries.