NIDDK Extramural Digital Pathology Repository System (HALO LINK)

近年来，新技术和数据处理能力已经消除了分子和组织病理学数据集整合的障碍。国家糖尿病、消化和肾脏疾病研究所的几个临床研究网络已经将数字病理库（DPRs）与数字整张幻灯片图像（WSI）结合起来，支持临床站点经典诊断标准的标准化。一项正在发展的研究是对这些数字集进行“挖掘”，以识别与疾病相关的特征。计算机辅助图像分析特征检测和特征识别是这类研究的关键组成部分。集中式NIDDK数字病理资源库将作为一个在线资源库，促进WSI的标准化存档，目标是为标准化、发现和验证研究工作提供受控访问。

In recent years, new technology and data processing capabilities have removed barriers to integration of molecular and histopathological data sets. Several clinical research networks across the National Institute of Diabetes, Digestive and Kidney Diseases extramural programs have put Digital Pathology Repositories (DPRs) into place with digital whole slide images (WSI) available to support standardization of classical diagnostic criteria across clinical sites. A developing line of investigation is the “mining” of these digital sets to identify features which correlate with disease. Computer assisted-image analysis for feature detection and feature recognition are key components of such investigation. The Centralized NIDDK Digital Pathology Repository will serve as an online repository to facilitate standardized archiving of WSI with the goal of providing controlled access for standardization, discovery and validation research efforts.