Improving physical function and quality of life in older adults with prediabetes utilizing interactive small-group resistance training through video conference technology

Vio是一个为55岁及以上的成年人设计的虚拟小组锻炼计划，在 日益流行的数字健身市场。Vivo提供3个关键的市场优势：1)个性化和 通过认证培训师的反馈提供个性化的现场培训体验，2)老年人社区 增强动力和社会支持，增加责任感和趣味性的锻炼者，以及3)Vivo 培训经验侧重于通过性能反馈、目标设定和 衡量体力消耗的系统。大多数老年人在两个年龄段之间的肌肉质量下降了30% 50比70。阻力训练是改善肌肉质量和功能的最有效策略 治疗骨质疏松症。Vivo的编程是基于科学证据，即使在没有 为满足个人的需求和功能水平而定制的慢性病、抵抗力训练 一种可行和循证的方法来改善身体机能，调节血糖处理，减少 跌倒的风险，并延长独立生活和老化的地方。到目前为止，已有92人参加了Vivo (年龄范围44-93岁)。在我们对34名8岁以上老年人(74%为女性；平均年龄为70.9岁；60-84岁)的初步研究中 我们观察到，在经过认证的培训师的带领下，我们进行了数周的活体训练(平均每人训练12小时) 通过30秒的手臂弯曲测试，上身力量提高了25.8%； 通过30秒椅子站立测试测量的下半身力量的改善；以及+28%的改善 耐力通过2分钟的抬膝测试来衡量。SBIR FastTrack的目标如下： 第一阶段目标1：评估当前静坐状态下的活体原型的可接受性、可行性和保真度 老年糖尿病前期患者里程碑1：评估a)出勤率、福利和障碍/促进者 参与度；b)易用性；c)总体满意度。里程碑2：评估培训师的忠诚度。 目标2 ：设计 并为Vivo 2.0里程碑1开发多功能平台原型：创建功能规范 以客户为中心的方法(结果、目标、遵从性、即将进行的锻炼)和社交参与度 支持。里程碑2：开发该平台的可点击原型。第二阶段目标1：设计和建造 Vivo 2.0平台--统一的Web/移动应用。里程碑1：评估原型的可用性。里程碑2： 在软件和硬件上迭代设计，以提高使用率、准确性和可用性。里程碑3： 根据新的原型和功能设计开发和测试最低可行的软件产品 包括移动前端和网络前端应用程序以及后端数据库。目标2：开展RCT以 确定Vivo 2.0诉等待名单控制的有效性。主要结果将是下肢的改变 12周后的力量通过30秒内站立椅子的次数和平均血糖水平来衡量 (HgA1c)。次要结果将包括生活质量的改善，以及坚持和社交的影响 对身体机能结果的投入。

Vivo is a virtual small group exercise program designed for adults 55 and over that is unique in the increasingly popular digital fitness market. Vivo offers 3 key market differentiators: 1) a personalized and individualized live training experience with feedback from a certified trainer, 2) a community of older adult exercisers which enhances motivation and social support, and increase accountability and fun, and 3) the Vivo training experience focuses on improving physical function using performance feedback, goal setting, and a system to measure perceived exertion. Most older adults experience a 30% loss in muscle mass between ages 50–70. Resistance training is the most effective strategy for improving both muscle mass and function and managing sarcopenia. Vivo’s programming is based on the scientific evidence that even in the absence of chronic disease, resistance training that is customized to meet the individual’s needs and level of functioning is a feasible and evidence-based approach to improve physical function, regulate glucose handling, reduce the risk for falls, and prolong independent living and aging in place. To date 92 people have participated in Vivo (age range 44-93). In our pilot study of 34 older adults (74% women; mean age 70.9 y; range 60-84y) after 8 weeks of participating in Vivo with a certified trainer (average of 12 hours of training per person) we observed +25.8% improvement in upper body strength as measured by the 30 second arm curl test; +25.9% improvement in lower body strength as measured by the 30 second chair stand test; and +28% improvement in endurance as measured by the 2-minute knee raise test. The aims for this SBIR FastTrack are as follows: Phase I Aim 1: Evaluate the acceptability, feasibility, and fidelity of current Vivo prototype in sedentary older adults with prediabetes Milestone 1: Assess a) attendance, benefits and barriers/facilitators of participation; b) ease of use; and c) overall satisfaction. Milestone 2: Assess trainer fidelity. Aim 2 : Design and develop a multifunctional platform prototype for Vivo 2.0 Milestone 1: Create functional specifications of the client-centered approach (results, goals, adherence, upcoming workouts), and social engagement and support. Milestone 2: Develop a clickable prototype of the platform. Phase II Aim 1: Design and build the Vivo 2.0 platform – a unified web/mobile application. Milestone 1: Assess prototype usability. Milestone 2: Iterate the design on the software and hardware to increase usage, accuracy and usability. Milestone 3: Develop and test a minimum viable software product based on the new prototype and functional design to include a mobile front-end and web front-end app and a backend database. Aim 2: Conduct a RCT to determine effectiveness of Vivo 2.0 v. wait list control. Primary outcomes will be change in lower extremity strength after 12 weeks measured by the number of chair stands in 30 seconds and average glycemic level (HgA1c). Secondary outcomes will include improvements in quality of life, and effect of adherence and social engagement on physical function outcomes.