PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
批准号:
2518996
负责人:
STUART A. KAUFFMAN
金额:
$8.4万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1993
资助国家:
美国
项目状态:
已结题
起止时间:
1993-08-01 至 1999-02-28
中文摘要
描述:PI建议制作生态系统的计算机模型,
单细胞生物 每个细胞内的一个过程网络
它的持久性和与环境的相互作用。 网络
通过化学物质的交换,
环境,形成一个全球网络。 在一些模型中,
突变可以改变这些网络,
细胞发生。 私家侦探想验证一个假设
的细胞将共同进化到一个相变,或边界,
秩序和混沌,在三个轴上:(1)动态轴,
表征细胞和生态系统中的状态变化,
短期或生理时间尺度;(2)共同进化轴,
表征细胞相互作用的策略;和(3)轴
分子多样性,用于表征新的
系统中的分子。 (我在这里使用“混乱”一词,
disorder --PI使用的术语--不是数学意义上的。 的
PI将生态系统建模为最简单的布尔网络
分析。
英文摘要
DESCRIPTION: The PI proposes to make computer models of ecosystems of
unicellular organisms. A network of processes within each cell mediates
its persistence and interaction with its environment. The networks
within individual cells are coupled by exchanges of chemicals through
the environment, forming a global network. In some of the models
mutations can modify these networks, and differential reproduction of
cells occurs. The PI wants to test the hypothesis that the population
of cells will coevolve toward a phase transition, or boundary, between
order and chaos, on three axes: (1) the dynamic axis, for
characterizing the changes of state in the cells and ecosystem on a
short-term or physiological time scale; (2) a coevolutionary axis, for
characterizing the strategies with which cells interact; and (3) an axis
of molecular diversification, for characterizing the evolution of novel
molecules in the system. (I use the term "chaos" here loosely to mean
disorder -- the term the PI uses -- not in the mathematical sense.) The
PI will model the ecosystem as a Boolean network in the simplest
analyses.
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PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
-
批准号:2187142
-
项目类别:
-
资助金额:$14.4万
-
财政年份:1993
-
负责人:STUART A. KAUFFMAN
-
依托单位:
PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
-
批准号:3308790
-
项目类别:
-
资助金额:$15.6万
-
财政年份:1993
-
负责人:STUART A. KAUFFMAN
-
依托单位:
PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
-
批准号:2187143
-
项目类别:
-
资助金额:$14.96万
-
财政年份:1993
-
负责人:STUART A. KAUFFMAN
-
依托单位:
PRINCIPLES OF ADAPTATION IN COMPLEX SYSTEMS
-
批准号:2187144
-
项目类别:
-
资助金额:$8.4万
-
财政年份:1993
-
负责人:STUART A. KAUFFMAN
-
依托单位:
ADAPTIVE EVOLUTION OF NOVEL FUNCTIONAL PEPTIDES
-
批准号:3297572
-
项目类别:
-
资助金额:$18.67万
-
财政年份:1988
-
负责人:STUART A. KAUFFMAN
-
依托单位:
ADAPTIVE EVOLUTION OF NOVEL FUNCTIONAL PEPTIDES
-
批准号:3297569
-
项目类别:
-
资助金额:$18.17万
-
财政年份:1988
-
负责人:STUART A. KAUFFMAN
-
依托单位:
ADAPTIVE EVOLUTION OF NOVEL FUNCTIONAL PEPTIDES
-
批准号:3297571
-
项目类别:
-
资助金额:$18.41万
-
财政年份:1988
-
负责人:STUART A. KAUFFMAN
-
依托单位:
海外基金