CANCER AND LEUKEMIA GROUP B

本申请寻求对CALGB调查员活动的支持， 通过加州圣地亚哥大学的 医学和附属机构，在癌症和 白血病B组。在未来的资助期内，我们会继续 为团体应计、团体科学和团体做出重大贡献 局 我们预计5年内应计费用将略有增加 即将到来的赠款周期，根据主要成员国 机构和我们的律师事务所，最低目标是250个累积案件 在申请的第一年。 我们希望女性 大约50%的病人都参加了临床试验 将更加重视让少数群体加入阿拉伯少数民族法律援助团 问题研究我们期望继续为 集团的智力生产力，通过设计和主持 协议，提出试点意见，供集团验证， 扩大，并通过刺激更多的基础研究组成部分，以集团 活动 我们计划继续为集团提供直接服务， 开发一个或多个新的CALGB相关参考实验室 肺癌的科学项目。 我们机构的成员希望 继续为集团科学/管理做出重大贡献， 委员会主席（Seagren -辐射模态委员会;绿色- 呼吸委员会）、核心委员会成员或常务委员会成员 集团科学和行政委员会。 我们将继续 作为我们的CCOP活动的临床资源和研究基地 在拉斯维加斯、内华达州和Kaiser CCOP圣地亚哥的CCOP附属机构， 致力于进一步加强我们的临床试验外联网络， 既保证收益，又激励和加强 智力活力和整体肿瘤学的最先进质量 在整个圣地亚哥地区提供的医疗服务。 持续参与 CALGB继续作为教师的重要教育工具， 加州大学圣地亚哥分校的研究员和众议院工作人员，退伍军人管理局医疗 中心，海军地区医疗中心，圣巴巴拉，霍格和 斯克里普斯诊所和研究基金会以及所有附属 参与血液学和肿瘤内科私人执业的人员， 参与我们的CALB活动。

This application seeks support for the activities of CALGB investigators, participating through the University of California San Diego School of Medicine and adjunct institutions, in the programs of the Cancer and Leukemia Group B. During the coming grant period, we will continue to make major contributions to group accrual, Group science, and group administration. We project a modest increase in accrual over the 5 year upcoming grant cycle based on enhanced activities both at the main member institution and in our adjuncts, with a minimum goal of 250 accrued cases in the first year of this application. We expect women to be approximately 50% of all patients we accrue to clinical trials. Increased emphasis will be placed on accruing minorities to CALGB studies. We expect to continue to contribute extensively to the intellectual productivity of the Group by designing and chairing protocols, presenting pilot observations for Group validation and expansion, and by stimulating more basic research components to Group activities. We plan to continue direct service to the group by developing one or more reference laboratories for new CALGB correlative science projects in lung cancer. Members of our institution expect to continue their major contributions to Group science/administration as committee chairs (Seagren - Radiation Modality Committee; Green - Respiratory Committee), Core Committee members, or members of standing Group scientific and administrative committees. We will continue to serve as a clinical resource and research base for CCOP activities of our CCOP adjunct in Las Vegas, Nevada, and at Kaiser CCOP San Diego and are working to further strengthen our clinical trials Outreach Network as a means to both assure accrual and stimulate and strengthen the intellectual vitality and state-of-the-art quality of overall oncology care delivered in the entire San Diego area. Ongoing participation in CALGB continues to serve as an important educational vehicle for Faculty, Fellows, and House staff at UCSD, the Veterans Administration Medical Center, the Naval Regional Medical Center, Santa Barbara, Hoag and Scripps Clinic and Research Foundation as well as for all the affiliated participants in private practice of hematology and medical oncology who share in our CALGB activities.