Mechanisms guiding pathfinding and positioning of cortical interneurons
Mechanisms guiding pathfinding and positioning of cortical interneurons
批准号:
nhmrc : 628517
负责人:
A/Pr Julian Heng
金额:
$41.45万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2010
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2010-01-01 至 2012-12-31
中文摘要
脑部疾病给澳大利亚带来了经济和社会负担,这些疾病的个人成本是不可估量的。当大脑发育时,神经元未能将自己定位在正确的位置,这导致了几种大脑的异常。我们的研究旨在发现神经元是如何运动的,以及什么因素影响这一过程。它提供了对正常大脑发育的理解,也提供了对大脑疾病形成过程中可能出现的问题的洞察。
英文摘要
Brain disorders place an economic and social burden on Australia and the personal costs of these illnesses are immeasurable. Several brain abnormalities are caused from the failure of neurons to position themselves in the correct location when the brain develops. Our study aims to discover how neurons move and what factors influence this process. It provides an understanding of normal brain development, as well as providing insight into what may go wrong in the formation of brain diseases.
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