Hematology Clinical Research Training Program

描述（由申请人提供）： 宾夕法尼亚大学的血液学研究培训项目成立于1978年，目前每年支持8名博士后学员。自24年前成立以来，我们计划的目标一直是确定对广泛定义的血液学学科感兴趣的个人，并帮助他们利用他们在基础，转化和以患者为导向的研究中的科学培训为独立研究者的学术生涯做好准备。最初，候选人几乎完全来自内科和儿科临床血液学肿瘤学培训计划的医生，但正如上次更新时所规定的那样，我们故意寻求非医生博士后学员，以提供背景和兴趣的混合。在资助的前24年中，87名博士后培训生和一名博士前培训生得到了支持：63名医学博士，12 MD-博士12位博士受训人员中有25名妇女和63名男子。在77名已完成培训的学员中，47名（61%）在学术机构担任全职职位，从事实验室或临床研究工作。另有7人（9%）主要从事临床实践，但有大学任命，并参与临床研究项目和兼职教学。我们的前学员谁已经完成培训三十四有校外研究资金。39人在24个机构任职，包括宾夕法尼亚大学、哈佛大学和国家卫生研究院。虽然从历史上看，该计划几乎完全支持博士后培训生，但我们现在寻求额外的支持，以便每年任命多达4名博士前培训生。这些额外的受训人员将主要来自宾夕法尼亚大学医学博士项目的医生-科学家受训人员-该项目也由该基金的首席研究员劳伦斯·布拉斯指导。博士前学生加入我们的计划反映了我们在吸引优秀学生在血液学相关研究的长期价值的信念，在他们的培训的早期点。 一个详细的计划，以确定适当的前和博士后候选人，为他们提供一个独立的职业生涯所需的研究和实验室技能，并在整个过程中指导他们包括在应用程序中。

DESCRIPTION (provided by applicant): The Hematology Research Training Program at the University of Pennsylvania was established in 1978 and currently supports 8 postdoctoral trainees per year. Since its inception 24 years ago, the goal of our program has been to identify individuals interested in the broadly-defined discipline of hematology, and to help them prepare for academic careers as independent investigators using their scientific training in basic, translational and patient-oriented research. Originally the candidates were drawn almost exclusively from physicians enrolled in the clinical hematology-oncology training programs in the Departments of Medicine and Pediatrics, but as specified at the time of the last renewal, we have deliberately sought non-physician postdoctoral trainees in order to provide a mix of backgrounds and interests. During the first 24 years of 'funding, 87 postdoctoral trainees and one pre-doctoral trainee have been supported: 63 M.D., 12 M.D.-Ph.D. and 12 Ph.D. Twenty five of the trainees are women and 63 are men. Of the 77 trainees who have completed training, 47 (61%) hold full-time appointments at an academic institution and are engaged in either laboratory or clinical research. An additional 7 (9%) are engaged primarily in clinical practice, but have university appointments and participate in clinical research projects and teaching part-time. Thirty four of our former trainees who have completed training have extramural research funding. Thirty nine hold faculty appointments at 24 institutions, including Penn, Harvard and the NIH. Although historically this program has supported postdoctoral trainees almost exclusively, we now seek added support in order to appoint up to 4 predoctoral trainees per year. These additional trainees will be drawn primarily from physician-scientist trainees in Penn's MD-PhD program - a program that is also directed by Lawrence Brass, the principal investigator on this grant. The addition of predoctoral students to our program reflects our belief in the long term value of attracting talented students in hematology-related research at an earlier point in their training. A detailed plan for identifying appropriate pre- and postdoctoral candidates, providing them with the research and laboratory skills needed for an independent career, and mentoring them throughout the process is included in the application.