Geostatistical software for health and exposure analysis

描述（由申请人提供）：该项目的总体目标是开发第一个地质统计软件，提供专门为健康数据分析设计的工具（例如，癌症发病率），提供：描述疾病的空间模式和确定变异的尺度，空间平滑和过滤以检测区域模式和热点，暴露数据的空间插值和随机建模，以及暴露和健康数据之间的尺度依赖关系的调查和可视化。 将编制教学材料，以促进卫生科学家使用这种相对较新的方法。 项目第一阶段将： 1.在已完成的模拟研究的坚实基础上再接再厉，进一步展示和评价地质统计学准确绘制地方和区域尺度潜在风险模式图以及调查疾病与环境因素之间的尺度依赖关系的能力; 2.进行需求分析，以确定最佳地统计方法和功能，纳入软件; 3.开发和测试算法和软件原型，以评估所提出的方法的可行性。

DESCRIPTION (provided by applicant): The overall objective of this project is to develop the first geostatistical software to offer tools that are specifically designed for the analysis of health data (e.g., cancer rates), providing: description of spatial patterns of disease and identification of scales of variability, spatial smoothing and filtering to detect regional patterns and hotspots, spatial interpolation and stochastic modeling of exposure data, and the investigation and visualization of scale-dependent relationships between exposure and health data. Instructional materials will be developed to promote the use of this relatively new methodology among health scientists. Phase I of the project will: 1. build on a firm foundation of completed simulation studies to further demonstrate and evaluate the ability of geostatistics to accurately map underlying local- and regional-scale risk patterns and to investigate scale-dependent relationships among diseases and environmental factors; 2. conduct a requirement analysis to identify the optimal geostatistical methods and functionalities to incorporate in the software; 3. develop and test algorithms and a software prototype to evaluate feasibility of the proposed approach.