Exposure Response Relationship In Hand Arm Vibration

暴露于振动工具会产生几个特征 影响上肢组织的疾病，这些疾病共同 手臂振动综合征（HAVS）国家研究所 职业安全和健康已经认识到暴露的重要性， 手臂振动响应关系的识别为三个之一 肌肉骨骼疾病协会（MSDC）的焦点。该提案代表 来自加拿大、芬兰、瑞典和美国的调查人员的联合计划， 美国将研究欧洲和北美的四个振动暴露队列。 他们是芬兰的Suomossalmi森林工人队列，沃尔沃卡车驾驶室 在Umea的装配工人，在Umea的电动船造船厂的工人， 康涅狄格州和康涅狄格州的牙科医生暴露在高频率 振动.牙科医生似乎经历了快速发作的伤害， 手指上的机械感受器这三个工业集团一直在 研究;其重新研究反映了利用现有暴露数据的意图， 并确保在健康影响已经量化的情况下参与队列 以及在哪里有可用的先前研究。后一点很重要，因为 建议的研究时间可能太短，无法理解受试者内部的变化。 工地选择反映了暴露变化和影响的纳入（沃尔沃） 和高频振动（牙科医生）。医学试验-激光 多普勒、冷激体积描记法、多频振动仪，以及 分离的手指神经传导--是复杂的， 生理学理解 暴露评估是这项研究中最复杂的部分。它包括 队列代表和个体的振动和生物力学评估 使用个性化数据记录仪和传感器监控日常工作程序 手套这一详细程度以前没有应用过，反映了 评估每日真实的时间暴露（经生物力学校正）的必要性 变量

Exposure to vibrating tools produces several characteristic disorders effecting tissues of the upper extremity, which collectively are termed the Hand-Arm Vibration Syndrome (HAVS). The National Institute of Occupational Safety and Health has recognized the importance of exposure and response relationships in hand-arm vibration by identification as one of three foci of the Musculoskeletal Disease Consortium (MSDC). This proposal represents the combined plan of investigators from Canada, Finland, Sweden and the United States to study four vibration-exposed cohorts in Europe and North America. They are the Suomossalmi forest worker cohort in Finland, the Volvo truck cab assembly workforce in Umea, the Electric Boat shipyard workforce in Connecticut, and Connecticut dental hygienists exposed to high frequency vibration. Dental hygienists appear to experience rapid onset injuries to mechanoreceptors in the fingers. The three industrial cohorts have been studied; their restudy reflects the intent to utilize existing exposure data, and to assure cohort participation where health effects have been quantified and where there are usable prior studies. The latter point is important because the proposed study period may be too brief to appreciate intra-subject change. Worksite selection reflects exposure variation and inclusion of impact (Volvo) and high frequency vibration (dental hygienists). Medical tests -- laser Doppler, cold challenge plethysmograpy, multi-frequency vibrometry, and fractionated digital nerve conduction -- are sophisticated and reflect physiologic understanding. Exposure assessment is the most complex component of this study. It includes vibratory and biomechanical assessment of cohort representatives and individual monitoring of daily work routines using individualized data loggers and sensor gloves. This level of detail, which has not been previously applied, reflects the necessity of assessing daily real time exposure corrected for biomechanical variables.