NCATS CLINICAL AND TRANSLATIONAL SCIENCE AWARDS (CTSA) PROGRAM: COORDINATION, COMMUNICATION AND OPERATIONS SUPPORT (CCOS)

CTSA计划的使命是更快地为更多患者提供更多治疗。在其二十多年的存在中，该计划已发展到60多个研究中心和试验创新网络等核心资源。为了帮助管理这样一个庞大的分布式结构并使其具有凝聚力，NCATS创建了一个协调中心（CC），其使命是促进协作科学团队的工作，提供后勤支持，并确保整个网络的信息无缝流动。目前的CTSA CC是领先创新与协作中心（CLIC），该中心于2017年获得拨款。 新的CTSA CC，协调，通信和业务支持（CCOS），代表了一种新的方法，利用合同机制，使NCATS能够更直接地控制CC的优先事项，并能够灵活快速地应对CTSA战略优先事项的变化。这种向合同的过渡将带来效率，并使我们能够提供我们认为CTSA需要的东西：一个最先进的卓越运营中心，将带来可复制的流程，技术卓越以及对将数据转化为知识的不懈关注。过渡也带来了挑战，我们正在通过组建一支具有学术中心的转化科学证书，CLIC的机构知识以及具有管理大型NIH研究联盟协调中心的高度相关经验的承包商的卓越运营来解决这些挑战。

The mission of the CTSA Program is to bring more therapies to more patients, faster. In its more than two decades of existence, the Program has grown to over 60 research Hubs and core resources such as the Trial Innovation Network. To help manage and bring cohesion to such a large and distributed structure, NCATS created a coordination center (CC) with the mission to facilitate the work of the collaborative scientific teams, provide logistical support, and ensure a seamless flow of information across the network. The current CTSA CC is the Center for Leading Innovation and Collaboration (CLIC), a grant awarded in 2017. The new CTSA CC, the Coordination, Communication and Operations Support (CCOS), represents a new approach that leverages a contract mechanism, which provides NCATS with more direct control over the priorities of the CC and the ability to pivot nimbly and rapidly to address changes in the strategic priorities for the CTSA. This transition to a contract will bring efficiencies and enable us to deliver what we believe the CTSAs need: a state-of-the-art operational center of excellence that will bring to bear reproducible processes, technological excellence, and a relentless focus on transforming data into knowledge. The transition also brings challenges, which we are addressing by assembling a team with the translational sciences credentials of an academic center, the institutional knowledge of CLIC, and the operational excellence of contractors with the highly relevant experience of managing coordinating centers for large NIH research consortia.