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Regulation of rodent energy metabolism, body weight and composition

Regulation of rodent energy metabolism, body weight and composition
啮齿动物能量代谢、体重和成分的调节
批准号：
10721862
负责人：
KEVIN HALL
金额：
$9.14万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10721862
关键词：
BehaviorBody CompositionBody WeightCollaborationsDataDevelopmentDiabetes MellitusEatingEndocrinologyEnergy MetabolismHumanInvestigationLaboratoriesLaboratory miceMolecularMusObesityOrganismPhysical activityRegulationRodentcostimprovedmathematical modelmicrobiotamouse model

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中文摘要
翻译
我们的实验室继续开发小鼠能量代谢和体重动态的数学模型。最近，我们帮助量化了所谓的“热中性区”和小鼠体力活动的能量消耗。这些项目正在与糖尿病内分泌学和肥胖分支的Marc Reitman博士实验室合作进行，并将提供对小鼠能量代谢调节及其与人类相似性和差异的更好理解。我们还与Barbara Rehermann博士的实验室合作，以更好地了解传统实验室小鼠与肠道中充满野生小鼠微生物群的“野生”小鼠之间的能量消耗差异。
英文摘要
Our laboratory continues to develop mathematical models of mouse energy metabolism and body weight dynamics. Recently, we helped quantify the so-called "thermoneutral zone" and the energy cost of physical activity in mice. These projects are being pursued in collaboration with Dr. Marc Reitman's laboratory in the Diabetes Endocrinology and Obesity Branch and will provide an improved understanding of the regulation of energy metabolism in mice and their similarities and differences with humans. We also collaborated with Dr. Barbara Rehermann's laboratory to better understand energy expenditure differences in conventional laboratory mice as compared to "wildling" mice whose guts have been populated by microbiota from wild mice.
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Interactions of diet, exercise, metabolism, and weight change in humans
Regulation of rodent energy metabolism, body weight and composition
Computational modeling of human metabolism, body weight and composition
Regulation of rodent energy metabolism, body weight and composition
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