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Computational modeling of human metabolism, body weight and composition

Computational modeling of human metabolism, body weight and composition
人体新陈代谢、体重和成分的计算模型
批准号：
8349651
负责人：
KEVIN HALL
金额：
$34.13万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8349651
关键词：
AffectAnorexia NervosaBehaviorBiological SciencesBody CompositionBody WeightBody Weight ChangesCachexiaClinicalClinical InvestigatorClinical ManagementClinical ResearchClinical SciencesCollaborationsComplexComputer SimulationDataDiseaseEatingEnergy IntakeEnergy MetabolismEngineeringGoalsHumanInterventionKnowledgeLifeMacronutrients NutritionMeasurementMetabolicMetabolic DiseasesMetabolismModelingObesityProspective StudiesPublishingRegulationResearchSystemUnited States National Institutes of HealthWasting SyndromeWeightdesignmathematical modelphysical scienceprogramsresearch studyresponsetoolvalidation studies

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中文摘要
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英文摘要
We continue to develop mathematical models of human metabolism and have conducted several validation studies using a variety of published data on the metabolic responses to overfeeding, underfeeding, and isocaloric changes in dietary macronutrients. Our models have been deployed as a clinical research tool in collaboration with NIH clinical investigators to help design prospective studies as well as plan and track clinical weight management programs. Our models are being applied to a variety of problems, from calculating the relationship between human weight change and food intake to calculating changes of free-living energy intake using frequent body weight measurements.
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Interactions of diet, exercise, metabolism, and weight change in humans
Regulation of rodent energy metabolism, body weight and composition
Computational modeling of human metabolism, body weight and composition
Regulation of rodent energy metabolism, body weight and composition
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