Bioinformatics, Statistical and Methodological Shared Resources Core

摘要-生物信息学、统计学和方法论核心 佛罗里达-加利福尼亚生物信息学、统计学和方法学（BSM）核心的主要目标 癌症研究，教育和参与（CaRE 2）健康公平中心是提供数据管理， 数据清理，数据存储，并将数据发布到公共数据库中，用于我们中心生成的所有信息。在 此外，它还将为所有癌症研究项目提供生物信息学、统计学和方法学支持 建议，以及未来的项目，将建立在他们和传播给所有关心2中心的成员， 科学家们及时地。我们将通过三个目标来实现这些目标：第一，我们将 提供生物信息学、统计学和方法学支持。这第一个目标建立了作业调度， 界面，以满足所有的CARE 2健康公平中心调查员的需求。我们将支持生物信息学， 跨项目和核心的统计问题。生物信息学支持将包括深入的质量控制， 评估来自多个平台的所有高通量测序数据，并促进公开访问 可用的数据集。统计和方法支持将包括从收集到统计数据的所有方面。 最先进的数据分析和解释，摘要，手稿和赠款准备。第二个目标是 增强和维护联合数据存储库资源，使CaRE 2成员能够进行交互。 第二个目标是确保所有数据都是高质量的，并传播给所有CARE 2中心成员， 科学界迅速。在第三个目标中，我们将提供生物信息学，统计学和方法学 支持和教育机会，以照顾2中心。第三个目标是在线开发 教育材料，BSMC的成员和客座专家将通过核心活动，如 所有CARE 2中心成员之间的研讨会系列和互动讲座。

ABSTRACT – BIOINFORMATICS, STATISTICAL AND METHODOLOGICAL CORE The primary goal of the Bioinformatics, Statistical, and Methodological (BSM) Core at the Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity Center is to provide the data management, data cleaning, data storage, and data release to public databases for all information generated by our Center. In addition, it will provide bioinformatics, statistical and methodological support for all the cancer research projects proposed, as well as future projects that will build upon them and disseminate to all CaRE2 Center members and the scientific community at large in a timely fashion. We will reach these goals through three aims: First, we will provide bioinformatics, statistical and methodological support. This first aim established the job scheduling and interfaces to meet the needs of all CaRE2 Health Equity Center investigators. We will support bioinformatics and statistical issues across the projects and cores. Bioinformatics support will include in-depth quality control and assessment of all high-throughput sequencing data from multiple platforms and facilitate access to publicly available datasets. Statistical and methodological support will consist of all aspects, from collecting to state-of- the-art data analysis and interpretation and abstract, manuscript, and grant preparation. The second aim will be enhancing and maintaining a federated data repository resource that enables the interaction of CaRE2 members. This second aim ensures that all data are of high quality and disseminated to all CaRE2 Center members and the scientific community promptly. In the third aim, we will provide bioinformatics, statistical and methodological support, and educational opportunities to the CaRE2 Center. This third aim focuses on developing online educational materials that BSMC's members and guest experts will present through the core events, such as seminar series and interactive lectures among all CaRE2 Center members.