PLAN FOR OBTAINING INFORMED CONSENT TO USE STORED HUMAN BIOLOGICAL MATERIALS

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本多中心方案旨在获得适当的知情同意书，以存档所有AACTG试验期间收集的剩余人体生物材料、血液、尿液、组织或其他体液。 可以采集额外的血液样本作为人类DNA的来源，用于可能的遗传分析。 这些样本是解决目前无法预测的未来研究问题的重要资源。 此外，标本代表独特的队列，未来可能无法重现。 所有艾滋病临床试验单位将入组不超过50，000例受试者。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This multi-center protocol was designed to obtain the appropriate informed consent to archive left-over human biological materials, blood, urine, tissue, or other body fluids, that are collected during all AACTG trials. An additional blood sample may be collected as a source of human DNA for possible genetic analyses. These samples are an important resource for addressing research questions in the future that cannot be anticipated presently. In addition, the specimens represent unique cohorts, which may not be reproducible in the future. No more than 50,000 subjects will be enrolled all across the AIDS Clinical Trials Units.