SOUNDTRAK DATA ACQUISITION AND ANALYSIS SYSTEM FOR OSDB

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 阻塞性睡眠障碍呼吸(OSDB)影响10%-23%的成年人和4%-10%的儿童。它与记忆力和注意力下降、车祸、高血压、斯托克斯病、心血管死亡以及儿童学习成绩差和认知能力受损有关。 目前，诊断OSDB需要多导睡眠图，这是在睡眠实验室进行的通宵研究。在儿童中，父母每晚打鼾史比多导睡眠图更能预测认知功能。由于目前还没有记录和测量几个晚上鼾声的方法，因此需要一种廉价的测试来诊断成人和儿童的OSDB。最近的研究表明，高频吸气音(HFIS)的出现可能与OSDB有关。 这项研究的目的是测试一种可在家中使用的小型便携式设备，以便在睡眠时检测HFIS。该设备将在GCRC多导睡眠监测睡眠实验室进行测试，并将其与实验室以前使用的HFIS检测设备进行比较。在这部分研究中，该设备检测OSDB的能力将与多导睡眠图OSDB参数进行比较。在使用这种新设备的同时，受试者也将在家里进行研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Obstructive Sleep Disordered Breathing (OSDB) affects 10-23% of adults and 4-10% of children. It is associated with decreased memory and concentration, auto crashes, hypertension, stokes, cardiovascular mortality and in children poor school and impaired cognitive performance. Currently, diagnosis of OSDB requires polysomnography which is an overnight study in a sleep laboratory. In children, a history of nightly snoring from the parent predicts cognitive function better than polysomnography. Since there is currently no method of recording and measuring snoring over several nights, there is a need for an inexpensive test to diagnose OSDB in both adults and children. Recent studies have suggested that the occurrence of high frequency inspiratory sounds (HFIS) may be related to OSDB. The purpose of this study is to test a small portable device that can be used in the home to detect HFIS during sleep. The device will be tested in the GCRC polysomnography sleep lab comparing it to a HFIS detection device previously used in the lab. The ability of the device to detect OSDB will be compared to polysomnographic OSDB parameters in this part of the study. Subjects will also be studied at home while using this new device.