DEPRESSION AND METABOLIC SYNDROME IN MEXICAN-AMERICAN WOMEN

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 我们将评估胰岛素敏感性，代谢参数和下丘脑-垂体-肾上腺（HPA）轴功能在30名抑郁症妇女参与我们的研究和30名年龄和体重匹配的健康对照妇女。本研究的目的是找出是否胰岛素抵抗和/或高血糖的趋势平行血浆皮质醇水平在抑郁症和抑郁症状的治疗是否改善这种状态的胰岛素抵抗。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will assess insulin sensitivity, metabolic parameters and hypothalamus-pituitary-adrenal (HPA) axis function in 30 depressed women participating in our study and in 30 age- and weight-matched healthy control women. The purpose of this study is to find out whether insulin resistance and/or hyperglycemic trends parallel plasma cortisol levels in major depression and whether the treatment of depressive symptoms ameliorates such a state of insulin resistance.