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EFFECTS OF LEPTIN REPLACEMENTS IN CHILDREN

EFFECTS OF LEPTIN REPLACEMENTS IN CHILDREN
瘦素替代品对儿童的影响
批准号：
7606773
负责人：
Julio Licinio
金额：
$2.95万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-02-21 至 2007-11-30
来源：
https://reporter.nih.gov/project-details/7606773
关键词：
AdultChildComputer Retrieval of Information on Scientific Projects DatabaseEndocrineFamilyFamily memberFundingGrantImmuneInstitutionLeptinMutationProtocols documentationResearchResearch Ethics CommitteesResearch PersonnelResourcesSourceUnited States National Institutes of Health

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will assess the endocrine and immune effects of leptin replacement in leptin-deficient children, from a consanguineous Turkish family. In a separate protocol (IRB # 01-01-019-03) we have studied adult members of this family. We now propose to study the effects of leptin replacement in children who are deficient in leptin due to a genetic defect. We hypothesize that leptin replacement will have significant effects on immune and endocrine function.
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