COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该核心是在其第五年的支持，其目标是提供一个环境，鼓励在转化神经科学的职业发展。 在此之前，核心基金提供津贴，以支持医学生（科茨先生、凯利先生、乔利诺女士、奎克女士和潘女士）的年度研究金，他们分别与Mawe、Wellman、Mawe、Cipolla和Eckenstein博士一起进行全职实验室研究。 科茨先生 发表了一篇论文，并在国家会议上作了介绍。 这一成功促使科茨先生进入弗吉尼亚大学的MD/PhD项目。 他已经成功地完成了他的博士培训和MD。 Kelley先生已毕业，目前是北卡罗来纳州大学的住院医师。 奎克的工作导致了一篇发表的论文，Ciolino女士是UVM病理学的住院医师。 去年，潘女士在埃肯斯坦博士的实验室进行研究，已经提交了一份出版物，预计她将合著另一份出版物。 已经组织了一个说明转化神经科学研究进展的课程。 该课程提供了对单一神经系统疾病研究的深入分析。 所承保的疾病每年都在变化。 过去的疾病实体包括帕金森氏病，多发性硬化症，精神分裂症和肌萎缩侧索硬化症。 明年的课程将侧重于脑血管疾病。 该课程包括12个每周一次的会议，从临床研究到基础分子方法。 来自神经病学，神经外科，心理学，医学和解剖学与神经生物学系的教师在这个团队授课的课程中合作。 此外，今年有四位外部演讲者贡献了演讲（罗伯特·布朗博士，哈佛大学;杰弗里·罗斯坦，约翰霍普金斯大学;杰里米·谢夫纳，纽约州立大学北部分校;乔安妮·圣皮埃尔，ALS协会）。 一个本科神经科学暑期奖学金计划已经建立。 本科生进行10周的研究，阅读主要文献，并参加COBRE教师的讲座。 今年有80多名学生（大多数来自与UVM不同的机构）申请，其中8人被录取。 我们过去的几个学生已经继续攻读博士学位。研究生课程，包括两个谁加入了我们的神经科学计划。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core is in its 5th year of support, with the goal to provide an environment encouraging career development in translational neuroscience. Previously, the core had provided the stipend to support an annual research fellowship for medical students (Mr. Coates, Mr. Kelley, Ms. Ciolino, Ms. Quick and Ms. Pan) who conducted full-time bench research with Drs. Mawe, Wellman, Mawe, Cipolla and Eckenstein, respectively. Mr. Coates published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVMs MD/PhD program. He has successfully completed his PhD training and MD. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. Ms. Quick's work has resulted in one published paper and Ms. Ciolino is a Resident in Pathology at UVM. Last year, Ms. Pan was conducting research in Dr. Eckenstein's laboratory, one publication has been submitted and she is expected to co-author another publication. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis, Schizophrenia and Amyotrophic Lateral Sclerosis. Next year's course will focus on Cerebrovascular diseases. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, four outside speakers contributed lectures this year (Drs. Robert Brown, Harvard University; Jeffrey Rothstein, Johns Hopkins University, Jeremy Shefner, SUNY upstate, and JoAnne St. Pierre, ALS association). An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. This year over 80 students (most from institutions different from UVM) apply, and 8 were accepted. Several of our past students have gone on to Ph.D. graduate programs, including two who have joined our Neurosciences program.