COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这一核心是其支持的第5个年头，目标是提供一个环境，鼓励职业发展的翻译神经科学。 此前，CORE为医科学生(科茨先生、凯利先生、乔利诺女士、奎克女士和潘女士)提供了年度研究奖学金，这些学生分别与马博士、威尔曼博士、马博士、西波拉博士和埃肯斯坦博士一起进行全日制长凳研究。科茨先生发表了一篇论文，并在国家会议上作了介绍。这一成功促使Coates先生进入UVMS MD/PhD项目。他已经成功地完成了博士培训和医学博士学位。凯利先生已经毕业，目前是北卡罗来纳大学的一名居民。奎克女士的工作已经发表了一篇论文，乔利诺女士是密歇根州立大学病理系的住院医生。去年，潘石屹在埃肯斯坦博士的实验室进行研究，已经提交了一份出版物，预计她还将与人合著另一份出版物。 已经组织了一门课程，说明翻译神经科学研究的进展。本课程提供了对单一神经疾病研究的深入分析。承保的疾病每年都在变化。过去的疾病实体包括帕金森病、多发性硬化症、精神分裂症和肌萎缩侧索硬化症。明年的课程将集中在脑血管疾病上。该课程包括每周12次的课程，范围从临床研究到基础分子方法。来自神经学、神经外科、心理学、医学系和解剖学与神经生物学系的教师在这门团队授课的课程中进行合作。此外，今年还有四位外部演讲者(哈佛大学的罗伯特·布朗博士、约翰·霍普金斯大学的杰弗里·罗斯坦、纽约州立大学北部的杰里米·谢夫纳和肌萎缩侧索硬化症协会的乔安妮·圣皮埃尔)发表了演讲。 一个神经科学本科生暑期奖学金项目已经建立。本科生进行为期10周的研究，阅读初级文献，并参加科布雷教职员工的讲座。今年有80多名学生(大多数来自与密歇根州立大学不同的机构)申请，其中8人被录取。我们过去的几名学生已经继续攻读博士研究生课程，其中两人已经加入了我们的神经科学项目。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core is in its 5th year of support, with the goal to provide an environment encouraging career development in translational neuroscience. Previously, the core had provided the stipend to support an annual research fellowship for medical students (Mr. Coates, Mr. Kelley, Ms. Ciolino, Ms. Quick and Ms. Pan) who conducted full-time bench research with Drs. Mawe, Wellman, Mawe, Cipolla and Eckenstein, respectively. Mr. Coates published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVMs MD/PhD program. He has successfully completed his PhD training and MD. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. Ms. Quick's work has resulted in one published paper and Ms. Ciolino is a Resident in Pathology at UVM. Last year, Ms. Pan was conducting research in Dr. Eckenstein's laboratory, one publication has been submitted and she is expected to co-author another publication. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis, Schizophrenia and Amyotrophic Lateral Sclerosis. Next year's course will focus on Cerebrovascular diseases. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, four outside speakers contributed lectures this year (Drs. Robert Brown, Harvard University; Jeffrey Rothstein, Johns Hopkins University, Jeremy Shefner, SUNY upstate, and JoAnne St. Pierre, ALS association). An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. This year over 80 students (most from institutions different from UVM) apply, and 8 were accepted. Several of our past students have gone on to Ph.D. graduate programs, including two who have joined our Neurosciences program.