SECRETION OF NGAL ON THE SKIN OF PATIENTS TREATED WITH ISOTRETINOIN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的是检测皮肤和血清中明胶酶相关脂蛋白(NGAL)的含量，并确定使用异维A酸治疗的患者皮肤上的NGAL是否增加。主要结果将是量化异维A酸治疗前后患者皮肤上NGAL的浓度，并确定这种蛋白质分泌增加的持续时间。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Gelatinase-Associated Lipocalin (NGAL) on the skin and in the serum (Pilot study) and to determine if there is an increase in NGAL on the skin of patients treated with isotretinoin. The primary outcome will be to quantify the concentration of NGAL on the skin of patients before and after treatment with isotretinoin and to determine the duration of the increase in secretion of this protein.