DIM STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 假设“生物反应DIM将与减少或清除HIV感染和非HIV感染的MSM中人类乳头瘤病毒的肛门感染有关，但没有异型增生的证据。主要目的”评估BR-DIM治疗12周后HPV的存在，第二目标是评估BR-DIM的安全性和耐受性。DBR-DIM对2-羟雌酮/16-羟雌酮代谢物尿液比例的影响

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypothesis " BioResponse DIM will be associated with a reduction or clearance of anal infection with human papillomavirus in HIV-infected and HIV-uninfected MSM without evidence of dysplasia Primary Objective " To evaluate the presence of HPV after 12 weeks of treatment with BR-DIM Secondary Objectives " To evaluate the safety and tolerability of BR-DIM. " To evaluate the effect of DBR DIM on the urinary ratio of 2-hydoxyestrone /16 ¿¿ hydroxyestrone metabolites