EFFECTS OF SLEEP DEPRIVATION ON PERFORMANCE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究调查了睡眠剥夺对几项被认为是衡量冲动行为的任务的影响，包括行为抑制，延迟折扣，冒险和注意力的测量。 先前的研究表明，睡眠剥夺会损害认知功能，包括与决策和自我控制相关的认知功能。 还有一些证据表明，吸烟者和不吸烟者对压力的反应不同。在这项研究中，我们假设被剥夺睡眠约36小时的受试者将在延迟折扣，冒险和行为抑制任务中表现得更冲动。 24名受试者参加了两个会议，一个晚上的睡眠剥夺（SD）后，一个正常的夜间睡眠（NS）。 两个阶段中的每一个都在两天内进行，从第1天晚上8点开始，到第2天晚上8点45分结束。主要结果测量是冲动任务的表现，评估睡眠剥夺影响的次要测量包括疲劳和生理测量的主观评级（心率、血压、唾液皮质醇水平和尿儿茶酚胺水平）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study investigated the effects of sleep deprivation on several tasks that are considered to be measures of impulsive behavior, including measures of behavioral inhibition, delay discounting, risk-taking and attention. Previous studies indicate that sleep deprivation impairs cognitive function, including cognitive functions related to decision-making and self-control. There is also some evidence that smokers and nonsmokers respond differentially to stress. In this study we hypothesized that subjects deprived of sleep for about 36 hours will perform more impulsively on delay discounting, risk-taking, and behavioral inhibition tasks. Twenty-four subjects participated in two sessions, one following a night of sleep deprivation (SD) and one after a normal night s sleep (NS). Each of the two sessions were conducted over two days beginning at 8 pm on Day 1 and ending at 8:45 pm on Day The primary outcome measures were performance on the impulsivity tasks, and secondary measures to assess the effects of the sleep deprivation included subjective ratings of fatigue and physiological measures (heart rate, blood pressure, salivary cortisol levels & urinary catecholamine levels).