Chemical and Molecular Pharmacology Training Grant

描述(由申请人提供)：这是一份申请支持化学和分子药理学培训计划的申请，该计划是2003年开展的一个新项目。 全基因组测序和无数蛋白质和信号转导途径的初步表征挑战着我们揭开细胞信号网络的设计原理，并了解药物如何影响它们。这一挑战将需要将严格的量化方法和概念--物理、化学、工程和信息学的方法和概念--应用于生物医学问题。因此，它还需要在该领域招募一名不同类型的学生，一名对定量科学感兴趣和有能力的学生。 化学和分子药理学培训补助金支持对化学和系统生物学博士项目中以数量为导向的学生的严格培训，该项目是从分子药理学博士项目演变而来的。该项目的正式课程作业不仅包括药代动力学和药效学等核心药理学学科，还包括从物理科学中提取的材料。此外，学生的研究工作处于跨学科科学的前沿。我们坚信，在生物和物理科学方面的强大培训对于培养未来化学和分子药理学的领导者是必不可少的。

DESCRIPTION (provided by applicant): This is an application for support for the Chemical and Molecular Pharmacology Training Program, a new venture undertaken in 2003. The sequencing of whole genomes and the initial characterization of myriad proteins and signal transduction pathways challenges us to unravel the design principles of cell signaling networks and understand how drugs can and do impinge upon them. This challenge will require the application of rigorous quantitative methods and concepts-those of physics, chemistry, engineering and informatics-to biomedical problems. It will therefore also require the recruitment of a different type of student to the field, a student with interests and abilities in quantitative science. The Chemical and Molecular Pharmacology training grant supports the rigorous training of quantitatively oriented students in the Chemical and Systems Biology Ph.D. program, which has evolved out of the Molecular Pharmacology Ph.D. program. The formal course work for the program includes not only core pharmacology disciplines like pharmacokinetics and pharmacodynamics, but also material drawn from the physical sciences. In addition, the students' research work is at the cutting edge of interdisciplinary science. It is our conviction that strong training in both biology and physical sciences is essential for training future leaders in chemical and molecular pharmacology